Special Issue "Cerebral Amyloid Angiopathy: Causes, Diagnosis and Treatment"
Deadline for manuscript submissions: closed (30 November 2019).
Interests: Cerebral amyloid angiopathy; Alzheimer’s disease; neurovascular unit; perivascular drainage
Cerebral amyloid angiopathy (CAA), which is characterized pathologically by the deposition of b-amyloid (Ab) in the walls of cerebral blood vessels, is increasingly gaining recognition for its role in stroke and Alzheimer’s disease (AD). Initially thought to be a relatively benign by-product, CAA is now known to induce cerebral haemorrhage and contribute directly to AD dementia. While post-mortem analysis is needed to confirm the presence of CAA, radiological and other biomarkers have significantly improved the diagnosis of CAA. Over the past few decades, preclinical and experimental models have generated significant new understanding of the role of the cerebrovasculature in the clearance of Ab from the brain. However, the exact mechanism(s) by which environmental and genetic factors contribute to the etiology of CAA remain unknown. Furthermore, there are currently no approved therapies for the specific treatment of CAA. This Special Issue will feature a selection of original research, review articles, and commentaries related to the current understanding of the molecular and cellular underpinnings of the etiology, diagnosis, and treatment of CAA.
Dr. Cheryl Hawkes
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Alzheimer’s disease
- Clearance mechanisms
- Risk factors