Molecular Studies of Bone Biology and Bone Tissue

Dear Colleagues,

This Special Issue focuses on physiological mechanisms of bone biology and bone tissue. Bone is a crucial tissue involved in a variety of metabolic tasks, including body support, organ protection, mineral deposit, and hematological functions. It has recently been shown that bone tissue has endocrine functions, releasing hormonally active compounds, such as osteocalcin. Bone tissue is constantly rebuilt via the bone remodeling process which involves osteoclast-mediated bone resorption, followed by osteoblast-mediated bone synthesis. The discovery of processes underlying the pathophysiology of metabolic bone disorders continues to be a major research focus, drawing experts from all medical fields. Furthermore, biomaterial-mediated immune responses regulate fundamental bone processes, such as osteogenesis, osteoclastogenesis, and inflammation, demonstrating the importance in biomedical applications.

This Special Issue, “Molecular Studies of Bone Biology and Bone Tissue”, aims to provide new knowledge on the regulatory mechanisms of bone regeneration by focusing on the biological interplay between stem cell differentiation, the immune system, and the involvement of novel materials.

Authors are invited to submit original research and review articles related to these topics.

Potential topics include the following:

• mechanisms of bone regeneration;
• innovative materials for bone regeneration;
• future bone tissue engineering applications;
• pathophysiology of metabolic bone diseases;
• role and use of stem cells in bone regeneration and repair;
• crosstalk between bone cells and immune cells;
• endocrine activities of bone tissue.

We welcome submissions of original articles, reviews, and communication. This Special Issue is supervised by Prof. Giovanna Iezzi, who is assisted by our Topical Advisory Panel Member: Dr. Emira D’Amico and Dr. Tania Vanessa Pierfelice (University of Chieti-Pescara).

Prof. Dr. Giovanna Iezzi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.