Whole-Cell System and Synthetic Biology, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 829
Special Issue Editor
Interests: synthesis biology; molecular biology; functional nucleic acids; biosensor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The whole-cell system has been of great interest recently and has advanced the analysis and manufacturing techniques in the past decade, benefitting from the development of molecular biology and synthetic biology. The understanding of cell metabolism and gene regulation at the molecular level is of particular significance. The understanding of how the whole-cell system is applied in analysis or manufacturing has progressed, but there is still a great deal to be learnt. Key issues gaps in the area are as follows: (1) Gene interactions and regulatory networks still need to be explored. (2) Technical approaches need to be upgraded to edit the whole cell system. (3) The performance of the whole-cell system needs to be improved. (4) How to effectively apply the whole cell system in food, the environment and other fields needs to be understood. Therefore, the aim of this Special Issue is to summarize and broaden the knowledge of new gene circuits, innovative molecular modification methods and the application of whole cell systems.
Authors are invited to submit original research and review articles that address the areas discussed above. Topics include but are not limited to the following:
- Identification and mining of new molecular networks in whole-cell systems;
- Methods for upgrading and the modification of whole-cell systems;
- Application of whole-cell systems in food, environment and other fields.
Dr. Jingjing Tian
Guest Editor
Manuscript Submission Information
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Keywords
- synthesis biology
- molecular biology
- functional nucleic acids
- biosensor
- CRISPR-Cas
- directed evolution
- whole-cell system
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