Innovative Delivery Technologies for Nucleic Acid Therapeutics: From In Vitro to In Vivo Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 May 2026 | Viewed by 2330
Special Issue Editor
Interests: DNA repair; nanobiotechnology; inflammation; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore cutting-edge delivery technologies for nucleic acid therapeutics, including mRNA, siRNA, ASOs, and plasmid DNA (such as CRISPR). We invite submissions that address the challenges and advancements in formulation and delivery strategies, from in vitro studies to in vivo applications. Topics of interest include, but are not limited to, the following:
- Novel nanoparticle formulations for nucleic acid delivery (e.g., lipid nanoparticles, polymer-based systems, hybrid nanoparticles);
- Targeted delivery approaches for specific organs, tissues, or cell types;
- Strategies for overcoming biological barriers and enhancing intracellular delivery;
- Comparative studies of different delivery systems in vitro and in vivo;
- Innovations in mRNA vaccine delivery and formulation;
- Advances in delivery technologies for gene editing tools (e.g., CRISPR/Cas9);
- Translational aspects of nucleic acid therapeutics.
We welcome original research articles, comprehensive reviews, and perspective pieces that contribute to advancing the field of nucleic acid delivery. Please note that the Special Issue is focused on molecular research, so pure clinical research will not be accepted. But clinical submissions with biomolecular experiments are welcomed.
Dr. Karim Daliri
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nucleic acid therapeutics
- nucleic acid delivery
- mRNA
- siRNA
- ASOs
- plasmid DNA
- CRISPR/Cas9
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