Molecular Research and Treatment of Oral Diseases

Dear Colleagues,

Oral diseases such as gingivitis, periodontitis, and oral cancer affect millions of people worldwide. Much research has been conducted to understand the pathogenetic mechanisms of these diseases and translate this knowledge into therapeutics. A thorough understanding of the pathogenesis, diagnosis, and treatment of different oral diseases is essential to maintain oral health. For decades, the study of oral pathogenetic mechanisms has been a major goal of basic research in the field of oral biology. In addition to clinical studies on patients and animal models, in vitro cell, culture systems have become precious tools to understand the molecular mechanisms underlying oral tissue morphogenesis as well as the above-mentioned oral diseases. In almost all oral diseases, the cells of the periodontal tissues and the oral cavity are damaged by external noxae. These noxae consequently lead to alterations in the cells’ physiology and impair the function of the whole tissue. The simulation of major pathogenetic factors, such as inflammatory stimuli or exposure to noxae led to valuable insights into the pathogenesis of oral diseases. In conjunction with clinical data, these findings are, nonetheless, the basis of the accurate diagnosis of disease entities as well as targeted, personalized treatment regimens in the future. This Topic will be entitled, “Molecular Research and Treatment of Oral Diseases”, and will focus on discussing pathogenesis, molecular targets, and therapeutics treatment for oral diseases. We welcome you to share experimental papers and the latest review articles with new data.

Dr. Dorina Lauritano
Guest Editor

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• oral medicine
• oral biology
• dentistry
• molecular biology