External Occlusion Procedures in Health and Exercise Performance

Dear Colleagues,

Ischemic preconditioning (IPC) is a conditioning method involving brief cycles of ischemia and reperfusion. It has gained increasing attention due to its excellent outcomes in heart, liver, and kidney protection against ischemia–reperfusion injuries. Furthermore, an increasing body of work explores the impact of local ischemic preconditioning (IPC) or remote ischemic preconditioning (RIPC) on sport performance, in terms of both the overall anaerobic and aerobic capacity as well as the molecular, biochemical, and local neuromuscular response.

However, despite the enormous efforts made by academic researchers, the effect of IPC or RIPC on performance remains inconclusive, with up to 60% of studies showing a positive effect and 36% and 4% showing no or negative effects, respectively. Therefore, new research focusing on the evaluation of the effectiveness, modification, and complexity of ischemic procedures are urgently needed. This Special Issue plans to give an overview of the most recent advances in the field of remote ischemic preconditioning and ischemic preconditioning and their applications in diverse areas. This Special Issue is aimed at providing selected contributions on advances in the modification of ischemic procedures, molecular mechanisms of ischemia action, and new potential applications of ischemic procedures in health and sport performance. Potential topics include, but are not limited to: IPC/RIPC procedures at the molecular level; biochemical adaptations induced by ischemic preconditioning; mechanisms of action; IPC/RIPC procedures as a way of improving adaptation to ischemic stress and increasing skeletal muscle performance; future perspectives for ischemic procedures in health and physical activity.

Dr. Jan Mieszkowski
Guest Editor

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