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Infectious Disease Reports
Special Issues
Epidemiology, Prevention and Research on Dengue Virus
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Epidemiology, Prevention and Research on Dengue Virus

A special issue of Infectious Disease Reports (ISSN 2036-7449). This special issue belongs to the section "Viral Infections".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1292

Special Issue Editor

Prof. Dr. Alessandro Bartoloni

E-Mail Website
Guest Editor
Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy
Interests: infectious diseases; neglected tropical diseases; antibiotic resistance; tropical medicine

Special Issue Information

Dear Colleagues,

Dengue infection is a significant global health threat, affecting tropical and subtropical regions in particular. As stated by the World Health Organization (WHO), it is one of the main causes of illness and mortality in several Latin American and Asian countries. It is estimated that about half of the world’s population is currently at risk of dengue, with 100 to 400 million cases being recorded annually. Climate change, population growth, international travel, and trade have resulted in important changes in the epidemiology and spread of the disease in recent years. Nevertheless, alongside the continuous spread and increase of dengue cases worldwide, new achievements in terms of management, prevention, and surveillance have been reached as well.

This Special Issue, "Epidemiology, Prevention and Research on Dengue Virus", will feature articles focused on current epidemiological scenarios of the dengue virus worldwide, as well as research works and updates on clinical and diagnostic aspects, vaccines, and other prevention strategies. Manuscripts structured as short communications, original research papers, and reviews on this subject will be considered by the Editorial Office and evaluated for their suitability to undergo revision.

The aim of this Special Issue of Infectious Disease Reports is to favor the rapid publication and dissemination of research data, with the objective of promoting the progress of scientific and clinical knowledge in the field of dengue infection. This will allow for the obtention of reliable and updated information to guide clinicians in the management and prevention of dengue, as well as policy makers in the implementation of adequate surveillance and control strategies.

Prof. Dr. Alessandro Bartoloni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Infectious Disease Reports is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dengue
  • vaccines
  • prevention
  • travel
  • arboviruses
  • epidemiology

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Published Papers (1 paper)

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Research

11 pages, 636 KB  
Article
Imported Dengue Fever in Milan, Italy: A Seven-Year Retrospective Study
by Margherita Eleonora Pieruzzi, Davide Mileto, Alessandra Helen Behring, Stefania Caronni, Alessandro Mancon, Luigi Vezzosi, Alberto Rizzo, Andrea Poloni, Andrea Gori, Andrea Giacomelli and Spinello Antinori
Infect. Dis. Rep. 2025, 17(5), 113; https://doi.org/10.3390/idr17050113 - 12 Sep 2025
Viewed by 720
Abstract
Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. Methods: We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the [...] Read more.
Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. Methods: We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive. Results: This analysis included 159 travelers with confirmed (n = 138; 86.8%) or probable (n = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30–50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3–6); 29.6% required hospitalization, with a median stay of four days (IQR 0–5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue. Conclusions: Dengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses. Full article
(This article belongs to the Special Issue Epidemiology, Prevention and Research on Dengue Virus)
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