How Genes Interact to Produce Function
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (1 January 2021) | Viewed by 5655
Special Issue Editor
Special Issue Information
Dear Colleagues,
Genes interact either through direct physical interactions, i.e., through their products, such as a protein complex, or indirectly as parts of cohesive networks or pathways. Ultimately, these interactions modulate a phenotype, a combination of all the epispastic, pleiotropic, and system level effects. Functional relationships among genes are studied at varying levels of resolution (molecular to organismal to population), in a variety of model organisms (yeast to mice to humans), and for a wide (and often ill-defined) set of functions.
As we still do not know the number of interactions of many genes, their products, and function(s), how context-dependent their functions are, and to what degree function and interactions are conserved, work to decipher these questions involves a broad set of fields and scientific approaches.
This Special Issue aims to highlight the variety of computational methods and tools that the functional genomics community uses to study gene interactions and predict function.
Dr. Sara BallouzGuest Editor
Manuscript Submission Information
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Keywords
- Functional genomics
- Systems biology
- Gene networks
- Interactomes
- Gene function prediction
- Co-expression
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