Special Issue "Mitochondrial Genomes: Genetic and Transcriptomic Studies"
Deadline for manuscript submissions: 15 January 2019
Mitochondria are small double membraned bound organelles found in almost every cell of all organisms. They are primarily responsible for energy production. Typically, there are approximately 100 mitochondria in each mammalian cell, and each mitochondrion harbors 2–10 copies of mitochondrial DNA. The human mitochondria genome is a double-stranded circular DNA molecule, consisting of 16,569 nucleotides. It contains 13 protein-coding genes, 22 transfer RNAs (tRNAs), and two ribosomal RNAs. Mitochondrial DNA (mtDNA) is maternally inherited, thus its genome is haploid. However, many sites in mitochondria DNA are heteroplasmic, containing two alleles. Mitochondrial DNA variants have been linked to various diseases and important biological processes, such as cancer, aging, etc. Mitochondrial research is on the rise across multiple fields in the medical sciences. Especially with the rise of high throughput sequencing, researchers now can examine mitochondria genome in unprecedented detail. In this Special Issue, we would like to invite researchers to share their latest work on the following mitochondria related (without being limited to) topics:
- Mitochondrial sequence analysis
- Mitochondrial mutations related to diseases or trait
- Mitochondrial mechanisms related to diseases or trait
- Mitochondrial heteroplasmy analysis
- Biotechnology aspects related to mitochondria research
- Bioinformatics, statistical aspects of mitochondria research
Prof. Yan Guo
Dr. Sergey Ivanov
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mitochondrial sequence analysis
- mitochondrial mutations related to diseases or trait
- mitochondrial mechanisms related to diseases or trait
- mitochondrial heteroplasmy analysis
- biotechnology aspects related to mitochondria research
- bioinformatics, statistical aspects of mitochondria research