Evolutionary Genetics of Insect Innate Immunity

Dear Colleagues,

Innate immunity in insects is constantly evolving to provide efficient protection against assaults by a wide range of microbial pathogens. Previous cutting-edge research using model insects together with genetic and genomic tools has led to the identification and characterization of distinct signaling pathways which are activated in response to microbial infections. These findings have led to a better understanding of the nature and regulation of insect innate immune processes that participate in the elimination of pathogens or the suppression of their virulence factors which are designed to evade immune surveillance. In turn, this crucial information has not only progressed the research field of insect innate immunity, but it has also rekindled interest in the innate immune system of mammals. The goal of the relevant scientific community is now to continue filling existing gaps in our knowledge about how microbial infections are sensed, how their presence is communicated both within and among cells and tissues of the insect host, and how they can be efficiently eradicated. This Special Issue in Genes on “Evolutionary Genetics of Insect Innate Immunity” will provide an excellent venue to report recent advances in this topic by publishing high-quality research articles and comprehensive reviews on current and future challenges.

Prof. Dr. Ioannis Eleftherianos
Guest Editor

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