Special Issue "RNA Target Prediction Methods"
Deadline for manuscript submissions: closed (30 June 2019).
Interests: cancer genomics and transciptomics; bioinformatics; systems biology; microRNAs; circular RNAs
Beyond their informational roles, RNAs play a wide range of functions in a variety of cellular processes and in disease mechanisms, mediated by the recognition and binding of target molecules. By base-pairing with DNA or other RNAs, RNAs regulate an array of processes through direct interactions, such as those involving the high pleiotropic microRNAs, and via competition or decoy functions, also in complex networks. Moreover, key to the function of many RNAs is their binding to proteins by sequence or folding motifs. Thousands of noncoding RNAs have been uncovered in the NGS era and the recent findings on circular RNAs further expanded the field. However, for many of these RNAs, the functions are still unknown, calling for an improved definition of RNAs’ interactions by experimental studies, high-throughput methods, and bioinformatic approaches. Far from being an easy task, the prediction of RNA targets represents a turning point in most research projects, since it allows the prioritization of RNAs for functional experimental study. A series of computational and methodological challenges are set by the complexity of RNA biology.
This Special Issue is dedicated to all the aspects of RNA target prediction with a focus on, but not limited to, computational methods, software, and resources. We welcome submissions of reviews, research articles, short communications, and “concept papers”.
Prof. Stefania Bortoluzzi
Dr. Enrico Gaffo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- RNA function prediction
- RNA–RNA interactions
- microRNA targeting
- RNA–protein binding
- RNA fold
- RNA motifs
- circular RNAs
- high-throughput data