Prebiotic Food and Human Health

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Nutrition".

Deadline for manuscript submissions: closed (21 November 2021) | Viewed by 3763

Special Issue Editor


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Guest Editor
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of Waters, Na Sádkách 1780, 370 05 České Budějovice, Czech Republic
Interests: human nutrition; dietary fibers; chronic diseases; encapsulation; delivery systems; emulsions; functional foods

Special Issue Information

Dear Colleagues,

Prebiotics, being non-digestible dietary fibers, can be defined as the “selectively fermented food constituents that permit specific modifications in the composition and/or performance of the gut microflora, which then confer significant benefits upon host health”. This includes all carbohydrate-derived compounds, primarily oligosaccharides, known to resist digestion in the human small intestine and reach the colon, where they are fermented by the gut microflora. Furthermore, inulin and oligofructose (OF), lactulose, resistant starch (RS), galactooligosaccharides (GOS), transgalactooligosaccharides (TOS), polydextrose, wheat dextrin, acacia gum, psyllium, banana, whole grain wheat, and whole grain corn have also shown prebiotic effects. The health benefits of prebiotics are associated with their capabilities to promote gut barrier function and host immunity, attenuating the growth of potentially pathogenic bacteria (e.g., clostridia) and increasing the production of SCFAs (i.e., acetate, butyrate, and propionate). Maintaining optimal levels of all these three SCFAs may have a broader range of health benefits, including impacts on the progression of conditions associated with metabolic syndrome, such as type 2 diabetes, obesity, and CVD.

For this Special Issue, we strongly encourage the submission of articles related to prebiotic dietary fibers and their potential role in human health, particularly in the control and prevention of chronic diseases.

Dr. Bakht Ramin Shah
Guest Editor

Manuscript Submission Information

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Keywords

  • prebiotics
  • formulations
  • gut microbiota
  • immunomodulation
  • health benefits
  • chronic diseases

Published Papers (1 paper)

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Research

12 pages, 3068 KiB  
Article
Amaranth Supplementation Improves Hepatic Lipid Dysmetabolism and Modulates Gut Microbiota in Mice Fed a High-Fat Diet
by Yongshou Yang, Rikako Fukui, Huijuan Jia and Hisanori Kato
Foods 2021, 10(6), 1259; https://doi.org/10.3390/foods10061259 - 01 Jun 2021
Cited by 7 | Viewed by 2872
Abstract
Diet-induced obesity is often associated with gut microbiota dysbiosis, lipid metabolism disorders, and chronic inflammation. Consumption of the pseudocereal Amaranthus mangostanus has multiple nutritional benefits. We investigated the effects of dietary amaranth on lipid metabolism and gut microbiota in high-fat (HF) diet-fed mice. [...] Read more.
Diet-induced obesity is often associated with gut microbiota dysbiosis, lipid metabolism disorders, and chronic inflammation. Consumption of the pseudocereal Amaranthus mangostanus has multiple nutritional benefits. We investigated the effects of dietary amaranth on lipid metabolism and gut microbiota in high-fat (HF) diet-fed mice. C57BL/6J mice were provided either a control diet, HF diet, or HF diet containing 10% amaranth powder (Ama) for 8 weeks. Ama supplementation significantly reduced the levels of triglycerides, total cholesterol, and phospholipids in the liver. Moreover, Ama supplementation downregulated the expression of lipogenesis-related genes including Hmgcr, Fdt1, and Sgle in the liver. The gut microbiota analysis showed that Ama supplementation reversed HF diet-induced reduction in bacterial diversity and richness. Additionally, beta diversity analysis of the inter-group variability in community structure showed a clear separation between the HF and Ama groups. Linear discriminant analysis effect size analysis revealed that 11 taxa were enriched in the Ama group, whereas 9 taxa were increased in the HF group. We found that family Porphyromonadaceae and unclassified S24-7 showed a strong positive and negative correlation with the lipid parameters, respectively. Taken together, these results indicated that dietary Ama may attenuate HF diet-induced deterioration of gut microbiota structure and hepatic lipid metabolism. Full article
(This article belongs to the Special Issue Prebiotic Food and Human Health)
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