Exploring Natural Antimicrobials and Antioxidants: Mechanisms and Applications in Enhancing Food Quality and Safety

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 30 December 2026 | Viewed by 802

Editors


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Guest Editor
Facultad de Ingeniería Química, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico
Interests: bioactive impregnation; food preservation; functional foods; mathematical modeling
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico
Interests: edible films; food quality; food safety; functional foods; shelf-life extension
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
SECIHTI-IPN Centro de Investigación en Biotecnología Aplicada, Tlaxcala, Mexico
Interests: dairy systems; natural antioxidants; food quality; food safety; emerging technologies

Special Issue Information

Dear Colleagues,

This Special Issue focuses on recent advances in the discovery, characterization, and application of natural antimicrobials and antioxidants as sustainable solutions for improving food quality, safety, and shelf life. With growing consumer demand for clean-label and chemical-free products, researchers and industry alike are turning to bioactive compounds derived from plants, microorganisms, and marine sources.

This Issue highlights the mechanistic insights into how natural compounds inhibit microbial growth and oxidative degradation, emphasizing molecular interactions, synergistic effects, and modes of action at cellular and biochemical levels. Contributions explore diverse application strategies, including incorporation into edible coatings and films, impregnation techniques for the enrichment of food matrices, and nanoencapsulation for enhanced stability and controlled release. Studies also address the integration of natural antimicrobials and antioxidants into packaging systems and food formulations, as well as the influence of processing technologies—such as drying, fermentation, and thermal treatments—on their stability, bioactivity, and functional performance.

Furthermore, the Issue discusses technological, regulatory, and sensory challenges associated with implementing natural preservatives in real-world food systems. Case studies demonstrate their effectiveness in extending shelf life, maintaining nutritional value, and ensuring microbial safety in various food matrices.

Overall, this Special Issue provides a multidisciplinary platform that bridges food chemistry, microbiology, and technology, advancing the development of natural, safe, and effective preservation strategies that align with global trends toward sustainable and health-oriented food production.

Prof. Dr. Irving Israel Ruiz-López
Prof. Dr. Carlos Enrique Ochoa Velasco
Prof. Dr. Genaro Gustavo Amador Espejo
Guest Editors

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Keywords

  • natural antimicrobials
  • natural antioxidants
  • food preservation
  • food safety
  • food quality
  • functional foods
  • bioactive compounds
  • edible coatings and films
  • processing effects
  • shelf-life extension
  • sustainable food systems

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Published Papers (1 paper)

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Research

15 pages, 8474 KB  
Article
A Novel Approach for Reducing Enteropathogens Using LAB-Fermented Whey Solution and UV-C Light-Activated Gallic Acid
by Luz Alejandra Márquez-Martínez, Xochitl Aparicio-Fernández, Genaro Gustavo Amador-Espejo, Paola Hernández-Carranza, María de Guadalupe Muñoz-Arenas, Irving Israel Ruiz-López and Carlos Enrique Ochoa-Velasco
Foods 2026, 15(15), 2589; https://doi.org/10.3390/foods15152589 - 23 Jul 2026
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Abstract
This study evaluates the combined antibacterial activity (AA) of lactic acid bacteria (LAB) and UV-C light-activated gallic acid (AGA) against two common enteropathogens (Escherichia coli and S. Typhimurium) in terms of microbial growth and survival during gastrointestinal simulation (GS). The LAB were [...] Read more.
This study evaluates the combined antibacterial activity (AA) of lactic acid bacteria (LAB) and UV-C light-activated gallic acid (AGA) against two common enteropathogens (Escherichia coli and S. Typhimurium) in terms of microbial growth and survival during gastrointestinal simulation (GS). The LAB were selected based on their capacity to ferment soy and whey concentrates in monoculture and co-culture. The resulting LAB-fermented medium (LABF) was evaluated for its antibacterial properties against enteropathogens and combined with AGA to determine its effects during the GS. Results indicated that the whey solution supported the highest growth of LAB co-culture (>107 CFU/mL). LABF showed AA in a dose-dependent manner, achieving >2-log reductions. Although AGA exhibited strong AA, when combined with LABF, its antimicrobial activity under GS was null, with a complete microbial recovery after 24 h of GS. Therefore, the application of LABF plus AGA in the in vitro gastrointestinal system needs further study to avoid loss of antibacterial activity during gastric transit. Full article
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