Natural Active Compounds in Foods: Screen, Sources and Health Benefits

A special issue of Foods (ISSN 2304-8158).

Deadline for manuscript submissions: 20 February 2026 | Viewed by 218

Special Issue Editors


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Guest Editor
College of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China
Interests: food natural products; medicinal and edible homologous variety resources; food nutrition; food health function; algae based food; metabolic engineering; synthetic biology; carotenoid metabolism; food safety; food toxicology

E-Mail Website
Guest Editor
College of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China
Interests: food natural products; essential oil; food nutrition; food health function; food safety; food toxicology; food packaging materials; postharvest preservation of fruits and vegetables

Special Issue Information

Dear Colleagues,

With the popularity of healthy lifestyles, individials’ attention to the nutritional functions of food has increased. Many bioactive compounds in natural products derived from food (including plants, animals, etc.) have important effects on the human body, promoting health and preventing disease. The functional active ingredients of food include various categories of compounds, such as polyphenols, flavone, alkaloids, saponins, sterols, volatile oils, polysaccharides, and so on. These ingredients have various effects antioxidant, anti-inflammatory, anti-aging, lipid-lowering, hypoglycemic, sedative hypnotic and anti-tumor effects, which aid in the management and prevention of some diseases and are widely employed in healthcare products.

Studying the effective active ingredients in food can help clarify its nutritional value, with these functional compounds also being widely used in the development of nutraceuticals, drugs and beauty and skincare products. Therefore, effectively utilizing food active ingredients has become an important aspect of research in the food industry. By utilizing modern biotechnology and molecular biology methods to screen bioactive compounds, the efficacy, signaling pathways, and targets of these components can be clarified at the cellular and animal levels, providing a powerful tool for in-depth research concerning food active ingredients.

Therefore, this Special Issue of Foods, entitled “Natural Active Compounds in Foods: Screen, Sources and Health Benefits" welcomes the submission of articles whose scope includes, but is not limited to, the following topics:

  • New methods for preparing active natural products and their biological significance.
  • The efficient discovery and diversity mining of the active compounds in food.
  • The biological synthesis and metabolic engineering of food active natural products.
  • The development and utilization of specialty foods, new food resources, and their active ingredients.
  • The screening and identification of Caenorhabditis elegans and food active ingredients.
  • The identification of natural food active product targets and signaling pathways at the cellular and animal levels.

Prof. Dr. Jianguo Jiang
Dr. Liang Zhu
Guest Editors

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Keywords

  • food active compounds 
  • activity screening 
  • compound preparation 
  • biological synthesis 
  • metabolic engineering 
  • new food resources 
  • Caenorhabditis elegans 
  • screening 
  • targets 
  • signal pathway

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Published Papers (1 paper)

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Research

16 pages, 1218 KB  
Article
Improvement in Physicochemical and Functional Properties of Insoluble Dietary Fiber from Rice Bran Treated with Different Processing Methods
by Yanxia Chen, Qin Ma, Fei Huang, Xuchao Jia, Lihong Dong, Dong Liu, Mingwei Zhang and Ruifen Zhang
Foods 2025, 14(17), 3116; https://doi.org/10.3390/foods14173116 (registering DOI) - 5 Sep 2025
Abstract
Rice bran represents an exceptional natural source of dietary fiber (DF), and its physicochemical properties and therapeutic potential are closely associated with its origin and processing methods. Herein, rice bran was subjected to extrusion, fermentation, and a combined treatment of fermentation and extrusion [...] Read more.
Rice bran represents an exceptional natural source of dietary fiber (DF), and its physicochemical properties and therapeutic potential are closely associated with its origin and processing methods. Herein, rice bran was subjected to extrusion, fermentation, and a combined treatment of fermentation and extrusion to explore the alternations in the structural, physicochemical, and functional properties of the resulting insoluble dietary fiber (IDF). All treatments induced substantial microstructural alterations in IDF, producing fiber matrices with enhanced porosity and looser architectures. The employed processing treatments significantly enhanced the functional properties of rice bran IDF over the unprocessed sample, with 1.37- to 1.78-fold increases in oil-holding capacity, 1.31- to 1.48-fold increases in cholesterol-adsorption capacity, 2.89- to 5.90-fold increases in α-amylase-inhibitory activity, and 2.41- to 3.70-fold increases in glucose-adsorption capacity. Among them, extrusion proved more effective than fermentation in enhancing the water-holding capacity, sodium cholate binding, and cholesterol-adsorption capacity of rice bran IDF. However, fermented rice bran-derived IDF exhibited the optimum α-amylase-inhibitory and glucose-absorption capacities among all employed IDF samples. These findings provide valuable insights for the development of rice bran-based functional foods with enhanced health benefits. Full article
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