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Diagnostics
Special Issues
Diagnosing, Treating, and Preventing Eye Diseases
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Diagnosing, Treating, and Preventing Eye Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 16 April 2026 | Viewed by 2618

Special Issue Editor

Dr. Ermete Giancipoli

E-Mail Website
Guest Editor
Eye Clinic, Hospital “V. FAZZI”, A.S.L. Lecce, 73100 Lecce, Italy
Interests: retinal disease; vitreoretinal surgery; cataract surgery; intraocular lens; cornea; glaucoma; neuro-ophthalmology; multimodal imaging; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Human vision is an extraordinarily refined process, strictly dependent upon the integrity of different structures within the eye. Whenever one of these structures is compromised as a result of a pathological process, the interplay between different portions of the eye is hampered, with a consequent and sometimes significant vision impairment. Chronic conditions like diabetic retinopathy, age-related macular degeneration and glaucoma can seriously affect patients’ quality of life and generate a significant socio-economic burden.  Prevention strategies, coupled with accurate diagnosis, are paramount for setting effective therapeutic interventions for our patients. Recent improvements in the field, including novel imaging technologies, machine learning, mini-invasive surgery and intraocular lens technology, abruptly changed our approach to eye diseases, both in terms of early detection of ocular abnormalities and introduction of individualized treatment modalities.

This Special Issue aims to bring together ophthalmologists, with a distinct set of expertise in different subfields of eye care, who may contribute to define the latest improvements in preventing, diagnosing, and treating eye diseases. 

Dr. Ermete Giancipoli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • retinal disease
  • vitreoretinal surgery
  • cataract surgery
  • intraocular lens
  • cornea
  • glaucoma
  • neuro-ophthalmology
  • multimodal imaging
  • artificial intelligence

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Published Papers (2 papers)

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10 pages, 2283 KB  
Article
Comparison of Short-Term Clinical Outcomes After Implantation of Two Monofocal, Aspheric Intraocular Lenses
by Jeewon Han, Yea Eun Lee, Nahyun Park, Chung Min Lee, Yoo Young Jeon, Hayoung Lee, Kyu Sang Eah, Yeji Yoon, Ho Seok Chung, Jae Yong Kim, Jiwon Jeong and Hun Lee
Diagnostics 2024, 14(24), 2862; https://doi.org/10.3390/diagnostics14242862 - 19 Dec 2024
Cited by 2 | Viewed by 1787
Abstract
Objectives: This study compared the visual outcomes and optical quality of two monofocal, aspheric intraocular lenses (IOLs; CT LUCIA 621P, Carl Zeiss Meditec; Eyhance ICB00, Johnson & Johnson Vision) by evaluating visual acuity, contrast sensitivity, and higher-order aberrations 1 month post-cataract surgery. Methods: [...] Read more.
Objectives: This study compared the visual outcomes and optical quality of two monofocal, aspheric intraocular lenses (IOLs; CT LUCIA 621P, Carl Zeiss Meditec; Eyhance ICB00, Johnson & Johnson Vision) by evaluating visual acuity, contrast sensitivity, and higher-order aberrations 1 month post-cataract surgery. Methods: In this retrospective, comparative study, 120 eyes (72 patients) that underwent cataract surgery with either CT LUCIA 621P (Lucia group) or Eyhance ICB00 (Eyhance group) implantation (60 eyes/group) were retrospectively investigated. Visual acuity at various distances and defocus curves were measured 1 month postoperatively. Optical quality was assessed by comparing contrast sensitivity and internal coma, spherical, and total aberrations by using iTrace (Tracey Technology), a ray-tracing-type aberrometer. Results: The visual acuity and defocus curves were similar between the two IOLs 1 month postoperatively. The Lucia group showed better contrast sensitivity at higher spatial frequencies: 12 cpd (p < 0.001, 1.32 LogCS vs. 1.02 LogCS) and 18 cpd (p = 0.009, 0.74 LogCS vs. 0.47 LogCS) unilaterally and 18 cpd (p = 0.044, 0.94 LogCS vs. 0.60 LogCS) bilaterally. Postoperative internal spherical aberration was significantly lower in the Lucia group (p < 0.001, −0.04 µm vs. −0.003 µm). Internal coma and total aberrations were similar. Conclusions: The visual acuity and defocus curves of the Lucia and Eyhance groups were comparable 1 month post-cataract surgery. The Lucia group’s superior contrast sensitivity and lower postoperative internal spherical aberration were due to differences in IOL designs, particularly the power variation patterns. Full article
(This article belongs to the Special Issue Diagnosing, Treating, and Preventing Eye Diseases)
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15 pages, 19144 KB  
Case Report
Purtscher-like Retinopathy in a Patient with Acute Alcoholic Pancreatitis and a Literature Review
by Vesela Todorova Mitkova-Hristova, Marin Anguelov Atanassov, Yumyut Remzi Idriz and Steffanie Hristova Hristova
Diagnostics 2025, 15(18), 2317; https://doi.org/10.3390/diagnostics15182317 - 12 Sep 2025
Viewed by 354
Abstract
Background and Clinical Significance: Purtscher-like retinopathy is a rare occlusive microangiopathy that causes sudden vision loss of varying severity. It presents with diverse retinal findings, such as cotton-wool spots, haemorrhages, and optic disc and macular edema, among others. A key characteristic is [...] Read more.
Background and Clinical Significance: Purtscher-like retinopathy is a rare occlusive microangiopathy that causes sudden vision loss of varying severity. It presents with diverse retinal findings, such as cotton-wool spots, haemorrhages, and optic disc and macular edema, among others. A key characteristic is the absence of trauma. This condition has been observed in patients with acute pancreatitis, renal failure, preeclampsia, HELLP syndrome, childbirth, and other systemic disorders. Case Presentation: A 35-year-old male presented with complaints of seeing spots in front of both eyes, with a duration of ten days following the initiation of treatment for acute alcoholic pancreatitis. On examination, best-corrected visual acuity (BCVA) in both eyes was 5/6. Fundus examination revealed multiple cotton-wool spots and haemorrhages located in the posterior pole and around the optic disc, more pronounced in the left eye, where the optic disc had blurred margins and the macular reflex was absent. Perimetry showed paracentral scotomas, and optical coherence tomography (OCT) revealed thickening and disruption of the inner retinal layers in the papillomacular region of both eyes. Fundus fluorescein angiography demonstrated adequate perfusion of the vascular network, with hypofluorescent areas in the arteriovenous phase, peripapillary and in the papillomacular zone, due to masking by cotton-wool spots and haemorrhages. Treatment included systemic antiplatelet agents, anticoagulants, and vitamins, along with topical non-steroidal anti-inflammatory drugs. Two months after the initial presentation visual acuity improved to 6/6 in both eyes. Follow-up OCT scans showed atrophy of the inner retinal layers corresponding to the previous cotton-wool spot and the areas of reduced light sensitivity on perimetry had decreased in size. Conclusions: Acute pancreatitis is the most common systemic condition associated with the development of Purtscher-like retinopathy. Timely diagnosis and management of the underlying systemic disease are essential for preventing ocular complications. Ophthalmological evaluation is necessary in patients with acute pancreatitis who present with visual symptoms in order to detect this often-overlooked rare condition. Full article
(This article belongs to the Special Issue Diagnosing, Treating, and Preventing Eye Diseases)
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