Designs

Cerebral palsy (CP) often causes mobility limitations that require assistive devices such as Ankle Foot Orthoses (AFOs) to enhance functional stability. This study aims to develop an optimized 3D-printed AFO design that improves comfort, structural durability, and production efficiency for children with CP. The research applies a Design of Experiment approach using the Taguchi method to optimize 3D printing parameters, supported by tensile testing to identify the best material configuration. Design alternatives were prioritized using the Analytical Hierarchy Process, while Finite Element Analysis was conducted to evaluate mechanical performance under physiological loading. The selected PETG configuration (33% infill density and 0.15 mm layer thickness) demonstrated improved tensile strength and flexibility, contributing to enhanced structural behavior. A prototype was produced and validated using the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST) questionnaire. Results showed higher overall user satisfaction for the optimized 3D-printed AFO compared to conventional devices, particularly in safety, comfort, and durability. The integration of optimized material parameters, systematic design evaluation, and user-centered assessment provides an effective pathway toward improving AFO performance and supporting the mobility and quality of life of children with cerebral palsy.

Multifunctional aerostructures that carry mechanical loadings while conducting electrical currents offer a promising approach to reduce the weight of Electrical Power Systems (EPS) of aircraft. However, Carbon Fibre-Reinforced Polymer (CFRP), when used for aerostructures, presents challenges in achieving multi-functionality due to anisotropic mechanical, electrical, and thermal properties. These properties are interdependent on both laminate-level design factors (fibre/resin choice, fibre volume fraction, stacking sequence, and electrode configuration) and system-level EPS constraints (allowable voltage drop, current, and installation geometry). State-of-the-art material design and selection methods lack a coupled mechanical–electro–thermal design and selection approach to overcome these challenges of a complex design space to enable identification of multifunctional CFRP (MF-CFRP) solutions. This paper presents the first methodology for the design and selection of MF-CFRP with combined electrical, structural, and thermal properties. The methodology integrates requirement capture, laminate layup determination, electro-thermal assessment, option ranking, and manufacturing route selection. The methodology couples laminate-level design factors with system-level EPS constraints and includes iterative loops to refine either the CFRP design or the EPS parameters when no solution initially exists. The methodology is demonstrated to enable the design of a CFRP component to conduct the electrical current as part of the 28 V_DC network in an aircraft. This case study demonstrates the value of the methodology to identify knowledge and dataset gaps necessary for MF-CFRP design, alongside enabling the design of MF-CFRP components to enable increased power density of weight-critical EPS. Although the case study focused on a 28 V_DC system, the methodology is generalisable to other aircraft electrical architectures since system-level electrical parameters are used within the methodology as adaptable inputs.

Glaucoma is recognized as the second leading cause of blindness globally and a primary cause of irreversible blindness, estimated to affect over 80 million patients worldwide, including 4.5 million in the United States. Though the disease is multifactorial, the primary cause is elevated intraocular pressure (IOP), which damages the optic nerve fibers that connect the eye to the brain, thus interfering with the quality of vision. Current treatments have evolved, which consist of medications, laser therapies, and surgical interventions such as filtering procedures, glaucoma drainage devices (GDDs), and current innovations of minimally invasive glaucoma surgeries (MIGS). This paper aims to discuss the history and evolution of the design and biomaterials employed in GDDs and MIGS. Through a comprehensive review of the literature, we trace the development of these devices from early concepts to modern implants, highlighting advancements in materials science and surgical integration. This historical analysis, ranging from the mid-19th century, reveals a trend towards enhanced biocompatibility, improved efficiency in IOP reduction, and reduced complications. We conclude that the ongoing evolution of GDDs and MIGS underscores a persistent commitment to advancing patient care in glaucoma, paving the way for future device innovations and therapeutic trends to treat glaucoma.