Special Issue "Ceramic and Metallic Biomaterials. Application in Medical Sciences"

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 20 August 2023 | Viewed by 2762

Special Issue Editor

Dr. Oana Dragos-Pinzaru
E-Mail Website
Guest Editor
National Institute of Research and Development for Technical Physics, 700050 Iasi, Romania
Interests: nanotechnology; nanomaterials; biocompatibility and biomedical applications of multifunctional nanoparticles; development of new materials for cancer detection and treatment; biosensors; solid-state materials chemistry; electrochemical synthesis; surface science

Special Issue Information

Dear Colleagues,

Nowadays, the development of new materials that can be used to treat, repair, diagnose, replace, or restore a function of the human body represents one of the key research topics for the worldwide scientists and medical industries. For example, metallic nanoparticles are studied for possible applications in biomedicine such as the manipulation of living cells (transportation, displacement, positioning, or cell separation) or cancer detection and treatment. Another important class of compounds that has attracted the attention of the scientific community is represented by ceramic biomaterials, which can be used for the replacement of various types of tissues (as implants or for the repair and reconstruction of various diseased parts of the body). The outperformance of a biomaterial is determined by its crystalline structure, microstructure, (such as grain size or porosity), biocompatibility, corrosion resistance, or mechanical properties. In this context, the development of new biomaterials with improved physical and mechanical properties and a low production cost, high availability, and good esthetics is imperative. This Special Issue, “Ceramic and Metallic Biomaterials. Application in Medical Sciences”, aims to explore the innovative progresses in the field of biomaterials used for the detection, treatment, or replacement of injured tissues, in order to develop practical solutions for clinical practice.

List of the potential topics:

  1. Metallic biomaterials for manipulation of living cells;
  2. New approaches in cancer detection and treatment;
  3. Advances in dental restorations materials;
  4. Tissue engineering: from idea to clinic.

Dr. Oana Dragos-Pinzaru
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ceramic biomaterials
  • metallic biomaterials
  • dental materials
  • medical application
  • biocompatibility
  • manipulation of living cells
  • cancer detection
  • cancer treatment
  • implants
  • tissue engineering

Published Papers (4 papers)

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Editorial

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Editorial
Special Issue: Ceramic and Metallic Biomaterials Nanoparticles for Applications in Medical Sciences
Coatings 2022, 12(7), 998; https://doi.org/10.3390/coatings12070998 - 15 Jul 2022
Cited by 1 | Viewed by 551
Abstract
Nowadays, the development of new materials that can be used to treat, repair, diagnose, replace, or restore a function of the human body represents one of the key research topics for the worldwide scientists and medical industries [...] Full article
(This article belongs to the Special Issue Ceramic and Metallic Biomaterials. Application in Medical Sciences)

Research

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Article
Tunnel Magnetoresistance-Based Sensor for Biomedical Application: Proof-of-Concept
Coatings 2023, 13(2), 227; https://doi.org/10.3390/coatings13020227 - 18 Jan 2023
Viewed by 281
Abstract
The aim of this work was to investigate and prove the possibility of the real-time detection of magnetic nanoparticles (MNPs) distributed in solid material by using a tunnel magnetoresistance-based (TMR) sensor. Following the detection tests of FeCrNbB magnetic nanoparticles distributed in transparent epoxy [...] Read more.
The aim of this work was to investigate and prove the possibility of the real-time detection of magnetic nanoparticles (MNPs) distributed in solid material by using a tunnel magnetoresistance-based (TMR) sensor. Following the detection tests of FeCrNbB magnetic nanoparticles distributed in transparent epoxy resin (EPON 812) and measuring the sensor output voltage changes at different particle concentrations, the detection ability of the sensor was demonstrated. For the proposed TMR sensor, we measured a maximum magnetoresistance ratio of about 53% and a sensitivity of 1.24%/Oe. This type of sensor could facilitate a new path of research in the field of magnetic hyperthermia by locating cancer cells. Full article
(This article belongs to the Special Issue Ceramic and Metallic Biomaterials. Application in Medical Sciences)
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Article
Synthesis and Characterization of Gold-Shell Magnetic Nanowires for Theranostic Applications
Coatings 2022, 12(11), 1755; https://doi.org/10.3390/coatings12111755 - 15 Nov 2022
Cited by 1 | Viewed by 677
Abstract
Increasing interest has been given in recent years to alternative physical therapies for cancer, with a special focus on magneto-mechanical actuation of magnetic nanoparticles. The reported findings underline the need for highly biocompatible nanostructures, along with suitable mechanical and magnetic properties for different [...] Read more.
Increasing interest has been given in recent years to alternative physical therapies for cancer, with a special focus on magneto-mechanical actuation of magnetic nanoparticles. The reported findings underline the need for highly biocompatible nanostructures, along with suitable mechanical and magnetic properties for different configurations of alternating magnetic fields. Here, we show how the biocompatibility of magnetic nanowires (MNWs), especially CoFe, can be increased by gold coating, which can be used both in cancer therapy and magnetic resonance imaging (MRI). This study provides a new approach in the field of theranostic applications, demonstrating the capabilities of core–shell nanowires to be used both to increase the cancer detection limit (as T2 contrast agents) and for its treatment (through magneto-mechanical actuation). The MNWs were electrodeposited in alumina templates, whereas the gold layer was electroless-plated by galvanic replacement. The gold-coated CoFe nanowires were biocompatible until they induced high cellular death to human osteosarcoma cells via magneto-mechanical actuation. These same MNWs displayed increased relaxivities (r1, r2). Our results show that the gold-coated CoFe nanowires turned out to be highly efficient in tumor cell destruction, and, at the same time, suitable for MRI applications. Full article
(This article belongs to the Special Issue Ceramic and Metallic Biomaterials. Application in Medical Sciences)
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Review

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Review
Biomaterials in Orthopedic Devices: Current Issues and Future Perspectives
Coatings 2022, 12(10), 1544; https://doi.org/10.3390/coatings12101544 - 14 Oct 2022
Cited by 1 | Viewed by 704
Abstract
In orthopedics, bone fixation imposes the use of implants in almost all cases. Over time, the materials used for the implant have evolved from inert materials to those that mimic the morphology of the bone. Therefore, bioabsorbable, biocompatible, and bioactive materials have emerged. [...] Read more.
In orthopedics, bone fixation imposes the use of implants in almost all cases. Over time, the materials used for the implant have evolved from inert materials to those that mimic the morphology of the bone. Therefore, bioabsorbable, biocompatible, and bioactive materials have emerged. Our study aimed to review the main types of implant materials used in orthopedics and present their advantages and drawbacks. We have searched for the pros and cons of the various types of material in the literature from over the last twenty years. The studied data show that consecrated metal alloys, still widely used, can be successfully replaced by new types of polymers. The data from the literature show that, by manipulating their composition, the polymeric compounds can simulate the structure of the different layers of human bone, while preserving its mechanical characteristics. In addition, manipulation of the polymer composition can provide the initiation of desired cellular responses. Among the implanting materials, polyurethane is distinguished as the most versatile polymeric material for use both as orthopedic implants and as material for biomechanical testing of various bone reduction and fixation techniques. Full article
(This article belongs to the Special Issue Ceramic and Metallic Biomaterials. Application in Medical Sciences)
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