Advanced Biomaterials, Coatings and Techniques: Applications in Medicine and Dentistry, 2nd Edition

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 25 May 2026 | Viewed by 1431

Special Issue Editors


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Guest Editor

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Guest Editor
Department of Oral Pathology, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania
Interests: oral medicine; oral pathology; dental materials; nanomaterials; biomaterials; oral microbiome; oral biofilm; oral cancer; nanomedicine; oral microenvironment; oral biomarkers
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Special Issue Information

Dear Colleagues,

We would like to invite you to submit a manuscript to this Special Issue, “Advanced Biomaterials, Coatings and Techniques: Applications in Medicine and Dentistry, 2nd Edition”.

The field of biomaterials is very extensive, encompassing both the materials themselves and their manufacturing methods, which are constantly developing.

The use of biomaterials for medical and oral applications is associated with specific issues concerning their biocompatibility, bio-integration, antimicrobial properties, corrosion resistance and long-term performance, which arise due to their close contact with human tissues. In the field of regenerative medicine, biomaterials are of great importance when used as scaffolds to promote cell growth and differentiation, resulting in the healing of tissue lesions.

Coatings are crucial to obtaining the most significant properties of biomaterials via surface modification, making them suitable for medical and oral applications.

This Special Issue aims to provide an updated outlook on the applications of biomaterials and coatings in medicine and dentistry and present innovative manufacturing technologies. It seeks to serve as a forum for researchers and scholars from across the world to report their research findings on this topic. We welcome research articles, reviews, and communications.

Prof. Dr. Lavinia Cosmina Ardelean
Prof. Dr. Laura-Cristina Rusu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • dental materials
  • novel technologies
  • protective coatings
  • bioactive coatings
  • antibacterial coatings
  • regenerative medicine

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Related Special Issue

Published Papers (3 papers)

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Research

16 pages, 5948 KB  
Article
Physicochemical, Microstructural and Biological Evaluation of Dressing Materials Made of Chitosan with Different Molecular Weights
by Zofia Płonkowska, Alicja Wójcik and Vladyslav Vivcharenko
Coatings 2025, 15(10), 1116; https://doi.org/10.3390/coatings15101116 - 24 Sep 2025
Viewed by 111
Abstract
The use of advanced wound dressings can significantly support the skin healing process by maintaining optimal conditions for tissue regeneration. In this study, foam-like dressings composed of agarose and chitosan, enriched with vitamin C, were developed using a simple and cost-effective freeze-drying method. [...] Read more.
The use of advanced wound dressings can significantly support the skin healing process by maintaining optimal conditions for tissue regeneration. In this study, foam-like dressings composed of agarose and chitosan, enriched with vitamin C, were developed using a simple and cost-effective freeze-drying method. Three types of chitosan with varying molecular weights (low, medium, high) were used to investigate their impact on the biological, physicochemical, and mechanical properties of the resulting foams. All fabricated biomaterials were biocompatible, non-toxic, and did not promote cell adhesion to their surfaces. The foams exhibited highly porous, hydrophilic microstructures with excellent fluid absorption capacity (~20 mL/g) and sustained vitamin C release over the first 24 h. Chitosan molecular weight had no significant effect on biological properties, but influenced samples’ wettability and mechanical parameters. The hydrophilic character of samples was observed in all tested biomaterials, with the strongest enhancement of hydrophilicity noted for the low molecular weight variant. The highest tensile strength was observed in samples prepared with medium molecular weight chitosan. The results indicate that among the analyzed variants, agarose-chitosan foam biomaterials containing medium molecular weight chitosan exhibited the most favorable properties, making them the most promising candidates for the treatment of wounds with excessive exudate. Full article
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15 pages, 4443 KB  
Article
Effects of Ti6Al4V Substrate Roughness on the Surface Morphology, Mechanical Properties, and Cell Proliferation of Diamond-like Carbon Films
by Chehung Wei, Bo-Cheng Wu and Min-Sheng Hung
Coatings 2025, 15(9), 1086; https://doi.org/10.3390/coatings15091086 - 16 Sep 2025
Viewed by 266
Abstract
This study investigated how Ti6Al4V substrate topography affects the performance of diamond-like carbon (DLC) coatings. Substrates with four finishes (unpolished, #100, #400, #800 grit) were coated, and their morphology, wettability, bonding structure, mechanical properties, and biological response were examined. Characterization was performed using [...] Read more.
This study investigated how Ti6Al4V substrate topography affects the performance of diamond-like carbon (DLC) coatings. Substrates with four finishes (unpolished, #100, #400, #800 grit) were coated, and their morphology, wettability, bonding structure, mechanical properties, and biological response were examined. Characterization was performed using AFM, SEM, contact angle tests, Raman spectroscopy, and nanoindentation. Biocompatibility was evaluated with A549 epithelial cells. DLC deposition reduced roughness while partly preserving surface features. Increasing Ra was associated with lower surface free energy and ID/IG ratios. It also correlated with higher hardness and modulus, reflecting greater sp3 bonding. Biological results, however, indicated that surface organization was more decisive than Ra magnitude. The #100-grit surface, with aligned anisotropic grooves, supported uniform wetting, protein adsorption, and sustained proliferation. In contrast, the unpolished and smoother surfaces did not maintain long-term growth. These findings suggest that anisotropy, rather than Ra alone, plays a key role in optimizing DLC-coated Ti6Al4V implants. Full article
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13 pages, 2316 KB  
Article
Atomic Layer Deposition of Zirconia on Cobalt–Chromium Alloys for Dental Prosthetics: Surface Functionalization Under MDR 2017/745
by Anna Ziębowicz and Mirosława Pawlyta
Coatings 2025, 15(9), 994; https://doi.org/10.3390/coatings15090994 - 27 Aug 2025
Viewed by 699
Abstract
The primary goal of this study was to assess the suitability of the proposed method for modifying the surface of cobalt alloys in dental prosthetics, taking into account the specific characteristics of the stomatognathic system during long-term use and their impact on physicochemical [...] Read more.
The primary goal of this study was to assess the suitability of the proposed method for modifying the surface of cobalt alloys in dental prosthetics, taking into account the specific characteristics of the stomatognathic system during long-term use and their impact on physicochemical properties and the adhesion of cariogenic bacteria such as Streptococcus mutans. Technological factors influencing the quality of the product and its final dimensional characteristics were considered, confirming or ruling out the possibility of iatrogenic errors (related to poorly shaped prostheses) occurring during laboratory fabrication. This study demonstrates that atomic layer deposition of ZrO2 on CoCr dental alloys results in a chemically stable, uniform, and protective surface layer, reducing ion release and improving surface quality. These improvements address key safety and performance requirements outlined in MDR 2017/745, supporting the use of ALD as a state-of-the-art technique for functionalizing dental prosthetic devices. Such coating development may influence the final quality of the denture and also verify its suitability for use in the oral environment (reducing the likelihood of denture stomatitis). Full article
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