Molecular Characteristics and Diagnostic Biomarkers in Tumors
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 86
Special Issue Editors
Interests: cancer genomics; DNA damage and repair; molecular tumor classification; genomic biomarkers; precision molecular diagnostics
Interests: lung carcinoma pathology; non-small cell carcinoma; small cell carcinoma; cytology; rapid on site evaluation; fine needle aspiration; small biopsy specimen
Special Issue Information
Dear Colleagues,
Tumor development and progression are driven by diverse molecular alterations that affect gene regulation, signaling pathways, metabolism, and interactions with the tumor microenvironment. Advances in genomic, transcriptomic, epigenetic, and proteomic technologies have enabled detailed molecular profiling of both solid and hematologic malignancies, revealing substantial biological heterogeneity within and across tumor types. These discoveries have provided critical insights into tumorigenesis and have accelerated the identification of diagnostic and prognostic biomarkers that inform clinical management.
Despite significant progress, important challenges remain in translating molecular findings into clinically actionable diagnostics. Further investigation is needed to clarify how specific molecular characteristics distinguish tumor subtypes, predict disease behavior, and guide therapeutic decision‑making. In particular, comparative analyses of tumor tissues, liquid biopsies, and emerging multiplex platforms are essential to improve early detection, risk stratification, and treatment monitoring.
This Special Issue welcomes original research articles and reviews focusing on the molecular characteristics and diagnostic biomarkers of tumors. Potential topics of interest include, but are not limited to, the following:
- Genomic, epigenetic, transcriptomic, and proteomic alterations in human tumors
- Molecular classification of tumors and its diagnostic and clinical relevance
- Discovery and validation of tissue‑based and liquid biopsy biomarkers
- Tumor microenvironment signatures and immune‑related diagnostic markers
- Emerging technologies and platforms for molecular tumor diagnostics
We hope this Special Issue will provide a comprehensive overview of current advancements and promote the integration of molecular insights into precision oncology.
Assoc. Prof. Anjali Seth
Prof. Dr. Israh Akhtar
Guest Editors
Manuscript Submission Information
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Keywords
- tumor molecular profiling
- diagnostic biomarkers
- precision oncology
- cancer genomics
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