Advances in the Epidemiology of Hemostasis Disorders in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Hematology & Oncology".

Deadline for manuscript submissions: 30 May 2026 | Viewed by 2

Special Issue Editors


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Guest Editor
Department of Pediatrics, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: pediatric hematology; bone marrow transplantation; bleeding disorders; coagulation disorders; general pediatrics
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Guest Editor
Pediatric Department, University of Medicine and Pharmacy "Grigore T. Popa", 16 University Street, 700115 Iasi, Romania
Interests: pediatric hematology; bleeding disorders; coagulation disorders; general pediatrics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hemostatic disorders in children, whether congenital or acquired, encompass a broad and complex spectrum of conditions associated with substantial morbidity and mortality. Beyond classical bleeding disorders—such as hemophilia, von Willebrand disease, platelet function abnormalities and vascular or connective tissue syndromes—disturbances of hemostasis may also manifest as thrombotic or microangiopathic complications, including cerebral or venous thromboses, disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS).

The epidemiology and underlying mechanisms of these disorders remain heterogeneous and incompletely elucidated. Recent advances in molecular genetics, biomarker identification and precision diagnostics have profoundly expanded our understanding of the pathways driving both bleeding and thrombosis in pediatric populations.

A comprehensive characterization of hemostatic disorders—from neonatal hemostasis to long-term complications of chronic diseases—requires an integrated, multidisciplinary approach involving hematologists, pediatricians, geneticists, immunologists and basic and translational researchers.

In this Special Issue, we welcome original research articles, reviews and case reports addressing advances in the epidemiology, diagnosis and management of pediatric hemostatic disorders. Contributions exploring molecular mechanisms, innovative therapeutic approaches and preventive strategies are particularly encouraged.

We look forward to your valuable contributions.

Prof. Dr. Anca Colita
Prof. Dr. Cristina Gavrilovici
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric hematology
  • hemostatic disorders
  • bleeding disorders
  • coagulation abnormalities
  • pediatric thrombosis
  • thrombotic microangiopathies
  • hemolytic uremic syndrome (HUS)
  • thrombotic thrombocytopenic purpura (TTP)
  • molecular and genetic mechanisms
  • precision diagnostics

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Published Papers

This special issue is now open for submission.
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