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Children
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Pediatric Digestive Tract Disease: Surgical Aspects
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Pediatric Digestive Tract Disease: Surgical Aspects

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Surgery".

Deadline for manuscript submissions: closed (20 December 2024) | Viewed by 2369

Special Issue Editor

Prof. Dr. Igor Sukhotnik

E-Mail Website
Guest Editor
Department of Pediatric Surgery, Dana Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, Affiliated to the Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel
Interests: general surgery; pediatric surgery; intestinal failure; short bowel syndrome; nutrition; metabolism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A new Special Issue in the open access journal Children (ISSN 2227-9067), entitled "Pediatric Digestive Tract Disease: Surgical Aspects", is now open for submissions. The aim and scope of this Special Issue is to establish a methodical approach to searching for everyday questions concerning surgical emergencies in childhood, diagnostic measures, therapeutic regimes, postsurgical care, and the prognostic values of pediatric surgical gastrointestinal diseases. Although this Special Issue cannot provide a substitute for a tutorial-type textbook on Gastrointesinal Surgery, it could be utilized by someone who is proficient in the fundamentals of pediatrics and pediatric surgery. It is not a systematic treatise on diseases of the gastrointestinal tract, but a collection of new and established facts that influence the natural course and results of certain surgical diseases and impact the relative success of various kinds of treatment. This Special Issue is as interesting and instructive to general physicians, family doctors and pediatricians as it is to pediatric surgeons.

Prof. Dr. Igor Sukhotnik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastrointestinal disease
  • surgery
  • children
  • upper gastrointestinal tract
  • lower gastrointestinal tract
  • hepatobiliary

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Published Papers (2 papers)

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Research

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12 pages, 415 KiB  
Article
Small Intestinal Bacterial Overgrowth in Children with Short Bowel Syndrome: Risk Factors, Clinical Presentation and Management—A Single-Center Experience
by Maja Velimirovic, Veronika Osterman, Ana Prislan and Tadeja Pintar
Children 2025, 12(3), 351; https://doi.org/10.3390/children12030351 - 11 Mar 2025
Viewed by 610
Abstract
Background: Children with short bowel syndrome (SBS) have abnormal intestinal anatomy, secretion, or motility, which can lead to small intestinal bacterial overgrowth (SIBO). In this paper, we describe our experience with SIBO in children with SBS, focusing on potential risk factors, clinical presentation, [...] Read more.
Background: Children with short bowel syndrome (SBS) have abnormal intestinal anatomy, secretion, or motility, which can lead to small intestinal bacterial overgrowth (SIBO). In this paper, we describe our experience with SIBO in children with SBS, focusing on potential risk factors, clinical presentation, and antibiotic treatment. Methods: A single-center retrospective descriptive cohort study of all episodes of clinically suspected SIBO in 16 children with SBS on home parenteral nutrition (HPN) between January 2018 and December 2022 was performed. Results: The mean small bowel remnant was 47 cm (SD = 31.5), with an absent ileocecal valve in 61.5% (8/13). Five children (31.2%) had at least 1 episode of clinically suspected SIBO, with a total of 25 episodes. The most common clinical presentation was diarrhea (76%), followed by meteorism (56%), loss of appetite (48%), flatulence (48%), weight loss (36%), abdominal pain (25%), and vomiting (12%). Fifty-six percent (16/25) of SIBO episodes were treated with one type of antibiotic, 36% (9/25) with two types, and 8% (2/25) with three types. Symptom resolution was achieved in 56% (14/25) of SIBO episodes after one course of antibiotic therapy. Two children (12.5%) had refractory and recurrent SIBO episodes treated with cyclic antibiotic regimens. Conclusions: SIBO can affect the ability of children with SBS to successfully wean off HPN. Diagnostic tests have innate challenges, and early clinical suspicion is paramount. Antibiotic therapy should be individualized considering the child’s age, gastrointestinal anatomy, and the risk of SIBO recurrence. Full article
(This article belongs to the Special Issue Pediatric Digestive Tract Disease: Surgical Aspects)
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Review

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12 pages, 2338 KiB  
Review
Updates in Biliary Atresia: Aetiology, Diagnosis and Surgery
by Mark Davenport
Children 2025, 12(1), 95; https://doi.org/10.3390/children12010095 - 16 Jan 2025
Viewed by 1407
Abstract
Biliary atresia (BA) is an obliterative disease of the bile ducts affecting between 1 in 10,000–20,000 infants with a predominance in Asian countries. It is clinically heterogeneous with a number of distinct variants (e.g., isolated, Biliary Atresia Splenic Malformation syndrome, Cat-eye syndrome, cystic [...] Read more.
Biliary atresia (BA) is an obliterative disease of the bile ducts affecting between 1 in 10,000–20,000 infants with a predominance in Asian countries. It is clinically heterogeneous with a number of distinct variants (e.g., isolated, Biliary Atresia Splenic Malformation syndrome, Cat-eye syndrome, cystic BA, and CMV-associated BA). Facts about its aetiology are hard to encounter but might include genetic, developmental, exposure to an environmental toxin, or perinatal virus infection. However, the cholestatic injury triggers an intrahepatic fibrotic process beginning at birth and culminating in cirrhosis some months later. Affected infants present with a triad of conjugated jaundice, pale stools, and dark urine and may have hepatosplenomegaly upon examination, with later ascites coincident with the onset of progressive liver disease. Rapid, efficient, and expeditious diagnosis is essential with the initial treatment being surgical, typically with an attempt to restore the bile flow (Kasai portoenterostomy (KPE)) or primary liver transplantation (<5%) if considered futile. Failure to restore bile drainage or the onset of complications such as recurrent cholangitis, treatment-resistant varices, ascites, hepatopulmonary syndrome, and occasionally malignant change are usually managed by secondary liver transplantation. This issue summarises recent advances in the disease and points a way to future improvements in its treatment. Full article
(This article belongs to the Special Issue Pediatric Digestive Tract Disease: Surgical Aspects)
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