Depression in Adolescents: Risk, Outcomes, and Intervention
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Mental Health".
Deadline for manuscript submissions: 15 November 2025 | Viewed by 55
Special Issue Editor
Interests: adolescent depression; gut–brain axis; gut microbiome; inflammation; probiotics and microbiome; targeted interventions; modifiable risk factors for depression; RCT; developmental psychopathology
Special Issue Information
Dear Colleagues,
Depression constitutes a major public health concern, with increasing prevalence from early to late adolescence. This condition can induce various challenges, including emotional, social, and physical health issues, and is a significant risk factor for suicide, the second leading cause of death among adolescents. As depression rates continue to rise, there is an urgent need for innovative strategies to identify risk factors, understand the underlying mechanisms of depression, and improve intervention efforts.
This Special Issue, “Depression in Adolescents: Risk, Outcomes, and Intervention”, welcomes original research and literature reviews that examine the diverse factors contributing to adolescent depression, including biological, psychological, developmental, and environmental influences (e.g., neurobiological changes, hormonal fluctuations, early trauma, peer relationships, socio-economic stress). We particularly seek studies that identify early warning signs, uncover mechanisms of risk, and propose innovative interventions that can help reduce the impact of depression among adolescents.
Contributions to this Special Issue should help identify key factors to consider in detecting depression early and guide the development of targeted interventions to more effectively address the growing incidence of depression in this vulnerable population.
Dr. Cherry Y. Leung
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- adolescent depression
- risk factors
- interventions
- biological risk factors
- psychosocial risk factors
- developmental
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