Regulation of Eukaryotic Cytochrome c Oxidase

Dear Colleagues,

A Topical Collection on “Regulation of Eucaryotic Cytochrome c oxidase” is planned to be published by the journal “Cells” this year. In this issue we intend to compile papers on the regulation of eucaryotic cytochrome c oxidase (CytOx) and mitochondrial respiration. Hence, we prefer to include papers presenting the regulation of CytOx activity having physiological significance. The detailed mechanisms of electron and proton transfer within the mitochondrially-encoded catalytic subunits I–III, which are similar to bacterial CytOx subunits I–III, will not be covered. Data on the regulation of CytOx activity by interaction with low molecular weight compounds (e.g. adenine nucleotides, calcium, zinc, di-iodothyronine) and with proteins (r.g., NDUFA4, Higda-1), regulation by expression of subunit isozymes, by phosphorylation and other chemical modifications, by supercomplex formation (e.g. respirasome) are welcome. In addition influence of subunit overexpression during cancerogenesis are wellcome.

Prof. Dr. Bernhard Kadenbach
Dr. Rabia Ramzan
Prof. Dr. Sebastian Vogt
Collection Editors

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