Special Issue "Dopamine Signaling: From Synapses to Behavior"

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 31 October 2020.

Special Issue Editor

Dr. Jérôme Baufreton
E-Mail Website
Guest Editor
Institut des Maladies Neurodégénératives, Université de Bordeaux, France
Interests: basal ganglia; cellular excitability; motor control; dopamine-dependent plasticity; Parkinson’s disease; synaptic transmission; dopaminergic neurons ; dopamine receptors

Special Issue Information

Dear Colleagues,

Dopamine (DA) is a catecholamine which is instrumental for learning and motivation. DA is synthesized and released by midbrain dopamine neurons which innervate motor and limbic circuits to regulate ongoing behaviors. DA acts on D1- and D2-like receptor families to dynamically modulate cellular excitability and synaptic plasticity in a circuit-specific manner, and to ultimately control motivated behaviors. Most recent studies have unraveled new mechanisms about DA signaling such as co-release of neurotransmitters by DA terminals and local control of DA release by receptors located on synaptic terminals independently of dopaminergic neuron firing activity. In addition, the use of genetically-encoded biosensors and subcellular approaches tends toward a re-evaluation of the anatomical organization of DA release sites and suggests a more rapid DA coding than originally described. These new findings profoundly alter our current knowledge of DA functions both in healthy and diseased conditions.

The aim of this Special Issue is to present articles that investigate molecular, synaptic, and circuit mechanisms underlying DA signaling in order to better understand how DA sculpts neuronal activity and DA-dependent behaviors.

Dr. Jérôme Baufreton
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • dopamine synthesis and release
  • dopamine receptors signaling
  • basal ganglia
  • limbic circuits
  • dopamine-dependent plasticity
  • motor control
  • learning
  • movement disorders
  • motivation
  • schizophrenia

Published Papers

This special issue is now open for submission.
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