The Regulation of Heterogeneous Cellular Population in Cancers: Single-Cell Analysis
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell and Gene Therapy".
Deadline for manuscript submissions: closed (30 December 2022) | Viewed by 3496
Special Issue Editor
Interests: NGS; cancer genomics; scRNA-seq; single-cell sequencing; liquid_biopsy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a common fatal human disease, and it often has a high degree of both intra- and inter-tumor heterogeneity. Moreover, it involves a complex tumor microenvironment, which consists of different immune and stromal components that interact with malignant cells to shape the favorable cellular and molecular landscapes that support tumor development. Traditional analytical strategies have their inherent limitations, and the emergence of single-cell sequencing enables comprehensive investigations to be conducted in an unprecedented level of detail. Given the merits of single-cell sequencing approaches in the study of human cancer, an increasing number of studies are adopting this strategic method.
For this Special Issue, we are focusing on various aspects of single-cell investigations in cancer, ranging from basic to translational perspectives. This Special Issue will act as a research platform, bringing together a collection of original research articles, reviews, and communications covering any topics related to single-cell investigations of cancer, including but not limited to, tumor heterogeneity, cellular and molecular landscapes, cell–cell interactions, mechanistic delineation, animal models and/or biomarker discovery.
Dr. Daniel Wai Hung Ho
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- single-cell investigation
- heterogeneity
- cell-cell interaction
- mechanism
