The Language of Neural Cells: Decoding Molecular Signaling in Neurodevelopmental and Neuro-Oncological Disorders
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editors
Interests: cell biology; cellular death; eryptosis; molecular signaling pathways; oxidative stress
Interests: cell biology; biochemical pathways; rare tumors; molecular signaling pathways; nanomedicine
Interests: cell biology; neurodegenerative pathways; molecular signaling pathways
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cells communicate through a sophisticated molecular language comprising signaling pathways that regulate vital processes such as growth, differentiation, disease progression and death. In the nervous system, this molecular dialogue is particularly intricate and tightly regulated, as it orchestrates brain development, synaptic plasticity, and the response to injury. In neurodevelopmental and neuro-oncological disorders, however, this language is often distorted. Mutations, epigenetic modifications, and the aberrant expression of signaling components can alter cellular communication, leading to disrupted development, uncontrolled proliferation, or neurodegeneration.
This Special Issue, "The Language of Neural Cells: Decoding Molecular Signaling in Neurodevelopmental and Neuro-Oncological Disorders", aims to explore the dysregulation of signaling pathways specifically in the context of complex disorders of the nervous system, including rare ones.
We invite original research articles, reviews, and perspectives that reveal the molecular mechanisms that contribute to resistance, and how targeted interventions can repair the altered cellular communication for better therapeutic outcomes. Topics may include, but are not limited to, receptor-mediated signaling in neural cells, transcriptional dysregulation in neurodevelopment and neurodegeneration, molecular mechanisms of resistance in CNS tumors, apoptosis induction, epigenetic regulation, and the therapeutic modulation of signaling networks.
Dr. Marilena Briglia
Dr. Alice Foti
Dr. Adriana C. E. Graziano
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neural cells
- molecular signaling
- neurodevelopmental disorders
- neuro-oncological disorders
- transcriptional dysregulation
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