Research on Extracellular Vesicles in Health and Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 25 February 2026 | Viewed by 1027
Special Issue Editor
Special Issue Information
Dear Colleagues,
Since Peter Wolf’s description of “platelet dust” in 1967, an extraordinary and long journey has been taken to define Extracellular Vesicles (EVs). From the early generic terms “microparticles” (MPs) or “microvesicles”, the International Society for Extracellular Vesicles (ISEV) has provided a precise classification and nomenclature. Nowadays, EVs’ molecular characterization (proteins, lipids, mithocondrial DNA, and miRNA) is a hot topic due to their emerging role as promising tools for providing information on pathogenic events and response to treatments in several clinical conditions. Circulating EVs play a crucial role, acting as mediators at both molecular and cellular levels; thus they could be considered a powerful, non-invasive “liquid biopsy” and a molecular magnifying glass for pathophysiological conditions. In this contest, EV isolation and characterization from cell lines and biological fluids remains a very challenging task for scientists to unravel novel mechanisms in cell-to-cell communication.
This Special Issue warmly invites original research articles and comprehensive review papers highlighting EVs’ involvment in health and disease conditions. We aim to explore their promising potential applications in biomarker discovery, therapeutic treatment, and translational medicine, emphasizing the importance of a “multidisciplinarity” approach for EV characterization that will open new frontiers in biomedical research and EV clinical application.
Dr. Maria Concetta Cufaro
Guest Editor
Manuscript Submission Information
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Keywords
- extracellular vesicles
- molecular mechanism
- biomarker discovery
- therapeutics
- translational medicine
- proteins
- DNA and RNA
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