Effect of Transcriptional Regulatory Factors and Signal Transduction on Cell Regeneration

Dear Colleagues,

Cellular regeneration, differentiation, and re-differentiation represent terms from basic research that have found application in therapeutics. In addition to many other attractive areas, a comprehensive discussion on myocardial cell regeneration has initiated cardiac cell therapy, involving interventions that optimize muscle cell regeneration, which is important for muscle injury repair, and cochlear sensory epithelium hair cell regeneration, which provides a therapeutic approach to recover hearing sensitivity.

Tissue regeneration studies focus on processes by which an injured organ regrows to offset the missed cells. This field has been at the focus of intense research because it represents the cornerstone of tissue engineering, the creation of artificial organs, and the generation of therapeutic stem cells for different types of mature cells. Efforts are dedicated to understanding organ regeneration, its molecular basis, signaling pathways, and the regulatory molecules required to procure a complete restoration.

In humans, limitations on the regenerative capacity of specific tissues and organs make it difficult to recover from diseases. The ultimate goal of cell and tissue regeneration is understanding the control of these events. Therefore, it is important to identify processes involved in the regulation of cell remodeling after cell damage to provide helpful information for challenging diseases.

The focus of the present Special Issue is on advances in cellular biology of regeneration, mechanisms and molecules involved in processes of repair, and the recovery of functionality after tissue damage. An ambitious goal is to provide ideas for future therapeutic approaches based on the current newest findings.

Dr. Ilja Vietor
Guest Editor

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