Organ and Tissue Fibrosis: Molecular Signals and Cellular Mechanisms—Second Edition
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 15 December 2025 | Viewed by 589
Special Issue Editor
Interests: fibrotic diseases; cancer and pathological angiogenesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of Cells is dedicated to the molecular signals and cellular mechanisms of organ and tissue fibrosis. Fibrosis is characterised as the formation and remodelling of scar tissue and is an end result of many conditions, such as injury and inflammation. Fibrosis leads to the loss of tissue and organ functions, while fibrotic disorders contribute to around 40% of all causes of mortality. Even though fibrosis occurs in the extracellular matrix, understanding the role of cells and molecular signals in organ fibrosis is important to enhance our knowledge of this pathological process and eventually develop effective treatments. This Special Issue will focus on various cellular and molecular mechanisms during fibrosis in various organs, such as inflammatory cytokine-induced cell transition into myofibroblasts. This Special Issue will contain both original research articles and reviews. Studies performed using in vitro, ex vivo and in vivo models are welcome.
Dr. Zhuo Wang
Guest Editor
Manuscript Submission Information
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Keywords
- fibrosis
- scarring
- cytokine
- myofibroblasts
- extracellular matrix
- growth factors
- mesenchymal transition
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