Role of Calpains in Health and Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 417
Special Issue Editors
Interests: mechanisms implicated in long-term synaptic potentiation and depression in hippocampus and other brain regions; regulation of glutamate receptors; role of oxygen free radicals in central nervous system; mechanisms underlying selective neuronal degeneration; computational neuroscience
Special Issue Information
Dear Colleagues,
Calpains comprise a large family of proteases that are tremendously conserved amongst species and are ubiquitously distributed in tissues. Since their discovery, there has been remarkable progress in understanding their diversity, structure, physiological roles, and involvement in a number of diseases. Today, more than 7,000 research articles focus on the calpains. Because of the increasing relevance of calpains to diseases such as eye diseases, neurodegeneration, muscle and metabolic diseases, wound healing, gastrointestinal disease, inflammation, and cancer, the field is continuously expanding. This Special Issue of Cells will provide the latest findings regarding the mechanisms underlying the roles of calpains in cell functions, the roles of different calpains under physiological and pathological conditions, as well as the translation of these findings into novel therapeutic approaches for several disorders. In addition, genetic studies are indicating that mutations in several calpains play critical roles in the etiology of several diseases, further extending the relevance of calpains in health and diseases.
Dr. Michel Baudry
Dr. Peter A. Greer
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- calpain
- physiology
- biochemistry
- disease
- mutation
- target
- inhibitor
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
