Neuroinflammation in Developmental Brain Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 1550
Special Issue Editors
Interests: inflammation; oxidative injury; neuroinflammation; neurodevelopment; hypoxia ischemia; endothelial injury
Interests: oligodendrocytes development; myelination; neuron-glia communication; developmental diseases
2. Department of Neurology, University of Louisville School of Medicine, Louisville, KY 40202, USA
3. Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA
Interests: autism; neurodevelopmental disorders; epilepsy; cannabinoids; axon guidance; genetics
Special Issue Information
Dear Colleagues,
Several neurodevelopmental disorders such as autism spectrum disorders, epilepsy, intellectual disability, attention deficit/hyperactivity disorders, communication disorders, cerebral palsy or schizophrenia have been linked to early life neuroinflammation and oxidative stress. Neuroinflammation is also a critical component of the CNS immunity. Persistent of this process becomes damaging, and ultimately perturbing cytokine-mediated normal immunity. Brain oxidative stress and uncontrolled microglial activation may result in immune dysfunction, vascular inflammation, disrupting the blood brain barrier, recruiting inflammatory cells and further escalating the inflammatory process and impacting CNS development. These processes have been shown to contribute to cognitive impairment, autism, attention deficit hyperactivity disorders, anxiety and depression. We invite original research articles, reviews, or shorter perspective articles on all aspects related to the theme of this special issue entitled: “Neuroinflammation in Developmental Brain Diseases”. Expert articles describing mechanistic, functional, cellular, biochemical, or general aspects of neuroinflammation and its consequences on CNS development and diseases are highly welcome.
Dr. Evelyne Gozal
Dr. Jun Cai
Prof. Dr. Gregory Neal Barnes
Guest Editors
Manuscript Submission Information
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Keywords
- neuroinflammation
- endothelial injury
- blood brain barrier
- microglia
- immune dysfunction
- oxidative stress
- autism spectrum disorders
- epilepsy
- cerebral palsy
- schizophrenia
- neurodevelopment
- neurovascular brain signaling
- inflammatory cytokines
- immune cells
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