CRISPR-Based Genome Editing Approaches in Cancer Therapy

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell and Gene Therapy".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 189

Special Issue Editor


E-Mail Website
Guest Editor
School of Dentistry and Medical Sciences, Charles Sturt University, Wagga Wagga, Australia
Interests: genome editing; CRISPR-technology

Special Issue Information

Dear Colleagues,

This Special Issue explores the role of CRISPR-based genome editing approaches in cancer therapy. Genome editing using RNA-guided programmable clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) nucleases has revolutionized genetic research, offering unparalleled speed, efficiency, and precision. Since its first application in mammalian cells more than a decade ago, the CRISPR toolbox has rapidly expanded, continuously offering novel genetic tools aiding disease modeling and therapeutic approaches, including in cancer.

For this Special Issue, we welcome submissions that harness novel advancements of CRISPR-technology aimed at improving cancer treatments, including but not limited to CRISPR-based genome editing in cancer cells, immunotherapy approaches using CRISPR technology, CRISPR diagnostics for early cancer detection and monitoring, or the use of functional genomic screens to identify novel cancer-driving genes. Studies highlighting the role of using CRISPR-based genome editing for anti-cancer treatments are of particular interest.

By highlighting innovative research and translational applications, we endeavor to advance our understanding of how CRISPR-based genome editing approaches can shape personalized anti-cancer treatments.

Dr. Martin Pal
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • CRISPR
  • genome editing
  • cancer therapy
  • precision medicine

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Published Papers

This special issue is now open for submission.
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