Molecular Bases Underlying Early Embryonic Development in Mammals

Dear Colleagues,

The early stages of mammalian embryonic development are characterized by a series of finely coordinated molecular and cellular events that determine the success of implantation and subsequent growth. Small alterations in these early processes can lead to impaired embryo viability and development. Understanding the molecular bases of these mechanisms is essential to identifying mechanisms underlying reproductive success and to reveal how disturbances lead to developmental defects or pregnancy loss.

Recent advances in molecular and cell biology are helping to uncover how gene expression, epigenetic regulation, and signaling pathways interact with metabolism and oxidative balance to support cell division, differentiation, and communication during early development. This Special Issue aims to gather original research and review articles that advance our understanding of the molecular and cellular mechanisms that affect the first stages of mammalian embryonic development. By integrating molecular, metabolic, and physiological perspectives, this Special Issue aims to integrate fundamental and translational insights, contributing to a deeper understanding of the factors that determine embryonic health and developmental success. We encourage researchers to submit manuscripts sharing molecular signalling, metabolic pathways, mitochondrial function, oxidative stress, or experimental models related to early embryos and developmental competence.

Dr. Rebeca González Fernández
Prof. Dr. Julio Ávila Marrero
Prof. Dr. Angela Palumbo
Guest Editors

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