Radiation-Induced Pathophysiological Changes, Molecular Mechanisms and Therapeutic Strategies

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 25 May 2026

Special Issue Editor


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Guest Editor
Radiobiology Research Laboratory, Singapore Nuclear Research and Safety Institute, National University of Singapore, Singapore 138602, Singapore
Interests: Health effects linked to continuous low-dose-rate radiation exposure, in particular on neurogenesis, neurodegeneration, neurological and neuropsychological disorders. The research aims to bridge critical knowledge gaps in low-dose-rate/dose radiation biology, informing safety standards and therapeutic interventions for at-risk populations.
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Special Issue Information

Dear Colleagues,

Radiation exposure plays a critical role in a wide range of medical, environmental, and occupational settings, leading to complex pathophysiological changes. Understanding the molecular mechanisms underlying radiation-induced tissue damage and cellular responses is essential for developing effective therapeutic strategies. This Special Issue aims to explore recent advances in the field, focusing on the molecular pathways activated by radiation, the resulting biological effects, and innovative approaches to mitigate damage. Contributions are welcomed on topics such as radiation biology, oxidative stress, DNA repair, cellular signaling, and novel therapeutic interventions. By integrating multidisciplinary research, this Issue seeks to provide a comprehensive overview of the mechanisms driving radiation-induced injuries and explore potential strategies to protect, repair, and restore affected tissues. We invite researchers, clinicians, and biotechnologists to submit original research articles, reviews, and case studies that advance our understanding of these critical processes and enhance the development of targeted therapies.

Thank you

Best wishes

Guest Editor

Dr. Feng Ru Tang,

National University of Singapore

Dr. Feng Ru Tang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • radiation biology, molecular mechanisms, radiation-induced tissue injury, oxidative stress, DNA damage and repair, cellular signaling pathways, therapeutic strategies, radioprotection, radiation-induced inflammation, radiotherapy adverse effects

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Published Papers

This special issue is now open for submission.
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