New Insight into Tumor–Tumor Microenvironment Crosstalk
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Microenvironment".
Deadline for manuscript submissions: closed (31 May 2025) | Viewed by 494
Special Issue Editors
Interests: cancer biology; cell proliferation; cancer biomarkers; tumor microenvironment; immunohistochemistry; histology
Special Issues, Collections and Topics in MDPI journals
Interests: cancer biology; cell proliferation; cancer biomarkers; tumor microenvironment; immunohistochemistry; histology
Special Issue Information
Dear Colleagues,
The tumor–microenvironment crosstalk is a symphony of cellular and molecular interactions that profoundly influence the behavior of cancer. This Special Issue aims to unravel the complex dialogue occurring at the interface of tumor cells and their surrounding milieu, a critical component of cancer progression. The dynamic interplay encompasses a multitude of factors, from the secretion of signaling molecules that modulate immune responses to the metabolic reprogramming that supports tumor growth. We will delve into the latest insights that highlight the reciprocal relationships between cancer cells and their microenvironment, including the role of extracellular matrix remodeling, the influence of immune cells on tumorigenicity, and the metabolic symbiosis that sustains the tumor's voracious demands. Understanding these cellular and molecular mechanisms is essential for deciphering the tumor's ability to adapt and thrive, offering avenues for the development of novel therapeutic strategies that target the very foundations of cancer's survival.
Both comprehensive reviews and original articles are welcome.
Prof. Dr. Piotr Dziegiel
Dr. Karolina Jablonska
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor–microenvironment interaction
- cancer therapy
- signaling
- extracellular matrix
- immune cells
- cell networks
- tumorigenesis
- cancer metabolism
- tumor cell plasticity
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