Special Issue "Catalyzed Synthesis of Chiral Amines "
Deadline for manuscript submissions: closed (15 August 2020).
Interests: enzyme engineering; biocatalysis and biotransformation; synthetic biology; unnatural amino acid mutagenesis
Chiral amines are valuable constituents of many important pharmaceutical compounds or their intermediates. It is estimated that nearly 50% of pharmaceutical drugs contain chiral amine scaffolds in their structures. The requisite amines are scarce in nature, and their industrial production mainly relies on the metal-catalysed, traditional organic synthesis. On the other hand, tremendous advancements in biocatalytic methods for chiral amines have been achieved during the last decades. Enzyme catalysis provides green and selective tools for the enantioselective synthesis of chiral amines.
This Special Issue aims to cover recent updates and novel trends in the synthesis of chiral amines. We invite the scientific community to submit their contributions in the form of original research papers and review articles that provide new insights and emphasize aspects of fundamental and applied research areas.
Contributions should be related, but not limited, to the following:
- Green synthesis of chiral amines
- Discovery of novel bicayalysts and/or engineering of known biocatalysts
- Development and application of novel immobilized biocatalysts
- Design and construction of new whole-cell biocatalysts
- Novel catalytic reactions for the synthesis of chiral amines.
Prof. Hyungdon Yun
Dr. Mahesh D. Patil
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Chiral amines
- Whole-cell biotransformations
- Immobilized enzymes
- Protein engineering
- Synthetic biology
- Cascade reactions