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Special Issue "Clinical and Genetics Aspects of Unexplained Left Ventricular Hypertrophy"
A special issue of Cardiogenetics (ISSN 2035-8148).
Deadline for manuscript submissions: closed (20 November 2022) | Viewed by 1169
Special Issue Editor
Interests: hypertrophic cardiomyopathy; aortic stenosis; echocardiography; heart failure; arterial hypertension
Special Issues, Collections and Topics in MDPI journals
Special Issue in Diagnostics: Diagnosis of Aortic Stenosis
Special Issue Information
The correct etiology of left ventricular hypertrophy (LVH) is often challenging for even the most experienced physicians. The 2020 AHA guidelines defined HCM as a disease in which morphologic expression is confined solely to the heart; it is characterized predominantly by LVH in the absence of another cardiac, systemic, or metabolic disease capable of producing the magnitude of hypertrophy evident in a given patient and for which a disease-causing sarcomere (or sarcomere-related) variant is identified, or the genetic etiology remains unresolved. However, as suggested by the 2007 ESC position paper, distinguishing primary and secondary disorders is not an easy matter, in that many of the primary LVHs can be associated with major extracardiac manifestations; additionally, the pathology in many of the diseases classified as secondary LVHs can predominantly (or exclusively) involve the heart. Hence, the first approach to LVH is done by physicians, that should orient not only biochemical and instrumental analyses but also genetic testing. Of note, the cost of excluding overall causes of LVH sine causa, before using genetics, is not feasible. In addition, genetics should be interpreted in the context of the clinical picture in a given patient. To clarify some of these steps, we have launched this Special Issue, inviting investigators to contribute with original research articles as well as review articles focusing on the understanding of clinical, and genetic approaches to LVH sine causa.
Prof. Dr. Maria Losi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cardiogenetics is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- aortic stenosis
- arterial hypertension
- heart failure
- hypertrophic cardiomyopathy
- inherited heart disease