Liquid Biopsy in Gastrointestinal Cancers

Dear Colleagues,

Liquid biopsies are of upmost importance in many cancer types due to the limited availability of the fresh tissue needed to perform molecular studies; in addition, this technique avoids the need for invasive tissue sampling. Furthermore, the need for new and effective biomarkers for early detection and patient monitoring is an important unmet clinical need in many digestive cancers such as pancreatic and gastric cancer. This issue will focus on topics concerning the use of liquid biopsies in all digestive tumors, including, but not limited to, early detection markers, novel treatment strategies and disease monitoring. Liquid biopsy marker studies may include the use of circulating nucleic acids, circulating tumor cells, metabolomics, methylation and microbiome markers, among others. Furthermore, studies using non-blood liquid biopsy samples such as saliva, feces and cyst fluid are highly encouraged, as well as studies focusing on pre-diagnostic cohorts. Review articles concerning the current state of the art and the future perspectives of liquid biopsies in digestive cancers are also encouraged.

Dr. Julie Earl
Dr. Bozena Smolkova
Dr. Agapi Kataki
Guest Editors

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