Dear Colleagues,

Since the first draft of the human genome was published twenty years ago, we witnessed astonishing technological advances and unceasing efforts, aimed at annotating every element of the genome. Despite the groundbreaking advances of recent years, deciphering the precise function of each coding or noncoding element and the intricate network of interactions that lie behind each cellular process is still an open challenge.

In this context, the systematic analysis of the function of each gene is pivotal to the identification of new possible therapeutic targets and to the characterization of the disease settings in which they might be enrolled. This concept is emerging in the field of new oncologic therapies, cancer being a broad collection of different diseases with multifaceted mechanisms of progression and drug resistance.

The development of new targeted therapies based on cancer genomics research requires systematic and multidisciplinary approaches that are now available and that will lead to the implementation of personalized treatments in the coming years.

This Special Issue of Cancers comprises both research articles and reviews of literature, including genomic research, discovery of new therapeutic targets through functional genomics, and pharmacological studies implementing those therapies

Dr. Valentina Sancisi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• genomics
• functional genomics
• target gene
• targeted therapy
• personalized medicine
• cancer