Resistance in Breast Cancer
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 17399
Special Issue Editors
Interests: HER2; breast cancer; gene expression
Special Issue Information
Dear Colleagues,
Advances in the understanding of tumor biology have led to the development of novel targeted therapies, which have markedly improved the outcomes of patients with breast cancer. Despite this progress, most women with metastatic disease do not respond to subsequent therapies, due to de novo or acquired resistance, and 20–30% of patients with early breast cancer relapse.
Moreover, breast cancer is, both clinically and biologically, a heterogenous disease, and not all patients experience the same benefit from the current systemic therapies. Early identification of biomarkers of response/resistance would help us to individualize treatment and spare patients from potentially ineffective and/or toxic therapies.
It is our pleasure to invite you to this Special Issue, entitled Resistance to Breast Cancer, which aims to summarize well-known mechanisms of resistance to the various therapies currently available, but also to identify and validate novel and clinically significant biomarkers for the early prediction of response/resistance to therapy and the prognosis of breast cancer.
In this Special Issue, original research articles and cutting-edge reviews are welcome. Research areas may include (but are not limited to) the following:
• Biomarkers of endocrine resistance;
• CDK 4/6 inhibitor resistance;
• Breast cancer heterogeneity;
• Mechanisms of resistance to anti-Her2 therapies;
• Mechanisms of resistance to ADCs;
• Mechanisms of immune evasion in triple-negative breast cancer;
• Biomarkers of response and resistance to immune checkpoint inhibitors in breast cancer;
• Mechanisms of resistance to PARP inhibitors.
We look forward to receiving your contributions!
Dr. Sonia Pernas
Dr. Romualdo Barroso
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomarkers
- endocrine resistance
- CDK 4/6 inhibitors resistance
- breast cancer heterogeneity
- mechanisms of resistance to anti-HER2 therapies
- immune checkpoint inhibitors
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