Intraoperative Radiotherapy in Cancer Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 15
Special Issue Editor
2. Institute of Research and Development of Advanced Radiation Technologies (radART), Paracelsus Medical University, 5020 Salzburg, Austria
Interests: IG-IOERT; sarcoma; GI tumors; SRS/SBRT
Special Issue Information
Dear Colleagues,
Intraoperative radiation therapy (IORT) is a special radiation technique that inherits the unique opportunity of guiding radiation therapy directly to the target during surgery, while sparing organs at risk by simply removing them from the area of interest. It comprises different methods (electrons, kV photons, HDR brachytherapy), which, however, all share the common feature described above. Although invented several decades ago, evidence remained scarce because of its limitation to a few expert centers in the world and the lack of standardization of treatment. Moreover, randomized trials and real-world data have shown conflicting results in the past, resulting in a lack of recognition of the technique within international guidelines. Some of these topics have dramatically changed with the invention of mobile linear accelerators, allowing a more widespread application of IORT. Moreover, intraoperative image guidance is now available, paving the way to more standardization.
This issue, therefore, aims at drawing attention of a broader community to the general possibilities and ongoing developments in the field of IORT, irrespective of the method. All aspects of IORT (clinical data, study protocols, reviews, physical, technical, and biological topics, including FLASH) are covered by the issue, and corresponding manuscripts are welcome.
Prof. Dr. Falk Roeder
Guest Editor
Manuscript Submission Information
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Keywords
- intraoperative radiation therapy
- image-guided IORT
- IOERT
- kV-IORT
- HDR-IORT
- FLASH
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