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The Impact of Community Context and Cancer Disparities

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Epidemiology and Prevention".

Deadline for manuscript submissions: closed (31 May 2025) | Viewed by 2156

Special Issue Editors


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Guest Editor
Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA
Interests: cancer risk; cancer disparities; social support

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Guest Editor
Institute for Population and Precision Health, Chicago, IL, USA
Interests: cancer risk; cancer disparities; social support

Special Issue Information

Dear Colleagues,

Despite significant progress being made in cancer prevention, detection, and treatment in recent decades, as cancer researchers, we all know that disparities in cancer outcomes based on race/ethnicity, income, geography, gender, and sexual identity are likely to widen without increased attention and improved intervention. The aphorism “a person’s zip code often matters more than their genetic code when it comes to their health” has proven true in the cancer disparities research domain and highlights community context as a key factor. A confluence of complex, interrelated, multilevel determinants, including socioeconomic, cultural, social, environmental, and neighborhood-level factors, are known to be drivers of health disparities across the cancer continuum. However, the community context—a major contributor to the unequal cancer burden experienced by racial, ethnic, economic, geographic, and sexual/gender minorities—has been understudied relative to individual-level factors. Likewise, many of these factors are underexplored in mechanistic cancer research. To advance cancer equity, especially in underserved and underrepresented populations, cancer prevention research demands greater insight into factors such as where we live and work, how connected we are in our community, and how much support we receive. To this end, we are seeking the submission of reports focused on the role of community in cancer disparities, including findings on social integration, social support, discrimination, isolation, engagement, resources and access, safety and violence, and other novel topics. Reports across the translational spectrum are needed, including basic research. In addition, given the heterogeneity among individuals within minority groups across the spectrum, we highlight the need for disaggregated community-level data, when possible, to develop effective strategies to achieve health equity.

For this Special Issue of Cancers, we welcome original research and review articles that offer insight into the role of community in cancer disparities and mitigation.

Dr. Briseis Aschebrook-Kilfoy
Dr. Jiajun Luo
Guest Editors

Manuscript Submission Information

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Keywords

  • community
  • contextual factors
  • neighborhood
  • social determinants
  • networks
  • social integration
  • social support
  • discrimination stressors
  • engagement
  • residence

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Published Papers (2 papers)

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Research

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13 pages, 1165 KiB  
Article
Colon Cancer Rates Among Asian Americans: A 2017–2021 Epidemiological Analysis
by Candice Do, Wei-Chen Lee, Christopher Huy D. Doan, Cathy Xie and Kendall M. Campbell
Cancers 2024, 16(24), 4254; https://doi.org/10.3390/cancers16244254 - 20 Dec 2024
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Abstract
Background: Colon cancer (CC) is a significant public health concern. With Asian Americans (AAs) representing a rapidly growing demographic in the United States, our study examined CC prevalence among AAs. Methods: The study merged the 2017–2021 Medical Expenditure Panel Survey and County Health [...] Read more.
Background: Colon cancer (CC) is a significant public health concern. With Asian Americans (AAs) representing a rapidly growing demographic in the United States, our study examined CC prevalence among AAs. Methods: The study merged the 2017–2021 Medical Expenditure Panel Survey and County Health Ranking. Our analysis calculated age-adjusted CC rates and examined its prevalence across states. Regression analyses were conducted to study county-level risk factors of CC. Results: The CC age-adjusted rate among AAs increased by five-fold, from 155 per 100,000 in 2017 to 753 per 100,000 in 2021. State-level disparities revealed the highest CC prevalence in Arkansas, Rhode Island, and New Hampshire. Not speaking other languages and having insurance were significantly associated with higher CC rates, suggesting barriers to preventions and greater use of screening (p < 0.05). County-level analysis identified lower CC prevalence in regions with a greater socioeconomic advantage (p < 0.05). Socioeconomic advantage seemed to facilitate higher screening rates, which then translated into higher CC rates. Conclusions: Our findings underscore the need for early preventions to address rising CC rates among AAs. Future research should also explore geographic factors to better understand the disparities in CC risk. Full article
(This article belongs to the Special Issue The Impact of Community Context and Cancer Disparities)
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Review

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20 pages, 336 KiB  
Review
End-of-Life Cancer Care Interventions for Racially and Ethnically Diverse Populations in the USA: A Scoping Review
by Carolyn J. Yee, Aashritha Penumudi, Terri Lewinson and Inas S. Khayal
Cancers 2025, 17(13), 2209; https://doi.org/10.3390/cancers17132209 - 1 Jul 2025
Viewed by 341
Abstract
Introduction: Racial and ethnic disparities in end-of-life (EOL) cancer care persist, leading to lower rates of advance care planning (ACP), reduced access to palliative care, and poorer patient outcomes for minority populations. While previous research has documented these inequities, less is known [...] Read more.
Introduction: Racial and ethnic disparities in end-of-life (EOL) cancer care persist, leading to lower rates of advance care planning (ACP), reduced access to palliative care, and poorer patient outcomes for minority populations. While previous research has documented these inequities, less is known about the specific interventions developed to address them, necessitating a comprehensive review of existing strategies aimed at improving EOL care for racial and ethnic populations. The objective of this scoping review is to examine the extent and characteristics of interventions and their outcomes designed to address racial and ethnic disparities in EOL cancer care in the United States. Methods: A comprehensive search of EOL cancer care interventions for minority populations was conducted in Ovid MEDLINE, CINAHL with Full Text (EBSCOhost), and Scopus (Elsevier) in September 2024. Two independent reviewers screened titles, abstracts, and full texts following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines, with inclusion limited to studies conducted in the US and published in English. Results: Of 3104 screened studies, 10 met the inclusion criteria. Participants enrolled were only from Latino (n = 6 studies) or Black (n = 4 studies) populations. We identified four types of interventions, including communication skills for patients, caregivers, researchers, and clinicians (n = 2), education programs for patients (n = 1), navigation and support programs for patients and caregivers (n = 3), and training programs for health workers and community leaders (n = 4). The most effective interventions were those that addressed linguistic barriers, integrated cultural values, and involved trusted community figures. Faith-based models were particularly successful among African American patients, while bilingual navigation and family-centered ACP interventions had the greatest impact in Latino populations. Conclusions: This review highlights (1) the importance of culturally tailored interventions for specific minority populations and (2) the limited number of such interventions, which primarily target only the largest minority groups. Full article
(This article belongs to the Special Issue The Impact of Community Context and Cancer Disparities)
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