Electroporation-Based Cancer Treatment. Selected Papers from the 4th World Congress on Electroporation
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (28 April 2023) | Viewed by 36699
Special Issue Editor
2. Center for Experimental Drug and Gene Electrotransfer (C*EDGE), Department of Clinical Oncology and Palliative Care, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark
Interests: Cancer; Oncology; Electroporation; Electrochemotherapy; Calcium electroporation; Exercise Oncology
Special Issue Information
Dear Colleagues,
Electric fields can cause cell permeabilization (electroporation), and this is increasingly being used in cancer therapy. Cell permeabilization may be transient (reversible), allowing for the passage of molecules, e.g.: chemotherapy (electrochemotherapy); ions; nucleotides, such as DNA; RNA. With higher field strengths, irreversible electroporation (IRE) can be achieved, leading to cancer cell death through the loss of cell integrity. The field is developing with different types of electric pulses as well as novel equipment, expanding indications.
This Special Issue brings together papers on basic and clinical research from presentations at the 4th world congress on Electroporation, held in Copenhagen in 2021. Electroporation based cancer therapy is being used for the treatment of cancer of different histologies and for tumors located, for example, in the skin, head and neck area, gastrointestinal tract, as well as in tumors in the liver. Basic research is developing our understanding of underlying mechanisms and expanding indications for treatment. This Special Issue bridges basic and clinical research in electroporation based cancer therapy, highlighting the developmental frontier within the field.
Prof. Dr. Julie Gehl
Guest Editor
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Keywords
- electroporation
- cancer
- electrochemotherapy
- calcium electroporation
- irreversible electroporation (IRE)
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