Single-Cell and Spatial Data Analytics in Cancers

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Informatics and Big Data".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 1

Special Issue Editors


E-Mail Website
Guest Editor
Vanderbilt University Medical Center, Nashville, TN, USA
Interests: data science, experimental design and analysis for single-cell and spatial omics

E-Mail Website
Guest Editor
Vanderbilt University Medical Center, Nashville, TN, USA
Interests: multi-omics integration; single-cell and spatial omics; transcriptional regulation

Special Issue Information

Dear Colleagues,

Single-cell and spatial omics technologies have significantly advanced cancer research by enabling high-resolution characterization of tumor biology at the cellular level. These sophisticated methodologies facilitate the identification of unique cellular subpopulations, monitor dynamic changes in cellular composition during tumor progression and therapy, and dissect intricate interactions within the tumor microenvironment. Such insights substantially enhance our understanding of genetic, molecular, and cellular mechanisms contributing to therapeutic resistance, thereby informing the development of targeted and individualized cancer treatments.

This Special Issue will present expert reviews and original research articles that demonstrate the application and impact of single-cell and spatial omics in cancer biology, addressing tumor heterogeneity, progression, immunological responses, immunotherapy, and tumor microenvironment dynamics across diverse cancer types and pan-cancer analyses.

Prof. Dr. Yu Shyr
Prof. Dr. Qi Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • single-cell and spatial omics
  • tumor heterogeneity
  • tumor progression
  • tumor microenvironment
  • cancer immunotherapy

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Published Papers

This special issue is now open for submission.
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