The Role and Advances of Hematopoietic Stem Cell Transplantation in the Management of Hematologic Malignancies
A Special Issue of Cancers (ISSN 2072-6694) belonging to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 June 2027 | Viewed by 27
Editor
Interests: allogeneic stem cell transplantation; management of AML patients; relapsed and refractory AML and other hematological malignancies; sequential conditioning regimens; donor lymphocyte infusion; allogeneic stem cell transplantation in IEI (Inborn Errors of Immunity) in adults; infectious complications; non-infectious complications; SOS/VOD; TA-TMA; GvHD; CAR T-cell therapy; CRS; ICANS; ICAHT; IEC-HS
Special Issue Information
Dear Colleagues,
Hematopoietic stem cell transplantation (HSCT) is an established method of therapy of various malignant and non-malignant hematological diseases, and sometimes it is the only curative strategy. There are different types of HSCT depending on donor source—autologous (using the patient’s own hematopoietic stem cells—HSC), allogeneic (using HSC from the related or unrelated donor—matched, mismatched or haploidentical) and syngeneic (using HSC from identical twin) transplants. Current indications and recommendations for these procedures are changing depending on the particular diagnosis and the steady progress in new therapeutic options. Despite unquestionable progress in transplantation procedures, they are still significantly associated with risk of serious infectious and non-infectious complications. The other issue is relapses after transplantation, especially in patients diagnosed with acute myeloid leukemia. There are not available standard treatment options in this situation and it remains an unmet clinical need. Thus, the objective of this Topic is to present the most recent advances in hematopoietic stem cell transplantation procedures, primarily allogeneic, with emphasis on complications and refractory cases as well as sharing our experience with novel therapeutic strategies in this difficult field.
We therefore are pleased to invite all Colleagues to send us their most promising basic, translational and clinical research in the field of hematopoietic stem cell transplantation. In this Special Issue, original research articles, narrative and systemic reviews, and short communications are all invited.
We look forward to receiving your contributions.
Dr. Agnieszka Tomaszewska
Guest Editor
Manuscript Submission Information
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Keywords
- hematologic malignancies
- hematopoietic stem cell transplantation
- myeloablative conditioning
- reduced-toxicity conditioning
- sequential conditioning regimen
- salvage therapy
- infectious complications
- non-infectious complications
- graft versus host disease
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