Modulation of the Tumor Microenvironment for the Treatment of Brain Tumors
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuro-oncology".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 246
Special Issue Editors
Interests: brain tumors; neuro-oncology; neurosurgery; neurotrauma; radiosurgery; immune-oncology; translational research; clinical trials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is becoming increasingly evident that modulation of the immune tumor microenvironment (TME) can rewire an immunosuppressive state to an immune-responsive milieu, allowing novel immune therapies to be used to treat primary and secondary brain tumors. An in-depth understanding of the key players surrounding modulation of this immune response could be a game changer in improving the normally dismal outcomes of malignant brain tumors. For this Special Issue of Brain Sciences, we are seeking original articles, clinical trials, and comprehensive reviews exploring novel mechanisms and treatments that rewire the TME of malignant primary and secondary brain tumors, priming the immune system for immunological tumor cell death, and/or leveraging novel combination therapies which lead to increased tumor cell death, decreased tumor burden, and prolonged survival.
Dr. Lam C. Fred
Dr. Cecile Maire
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- immuno-oncology
- primary brain tumors
- metastatic brain tumors
- neuro-oncology
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