Modulation of the Tumor Microenvironment for the Treatment of Brain Tumors
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuro-oncology".
Deadline for manuscript submissions: 31 August 2026
Special Issue Editors
Interests: brain tumors; neuro-oncology; neurosurgery; neurotrauma; radiosurgery; immune-oncology; translational research; clinical trials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is becoming increasingly evident that modulation of the immune tumor microenvironment (TME) can rewire an immunosuppressive state to an immune-responsive milieu, allowing novel immune therapies to be used to treat primary and secondary brain tumors. An in-depth understanding of the key players surrounding modulation of this immune response could be a game changer in improving the normally dismal outcomes of malignant brain tumors. For this Special Issue of Brain Sciences, we are seeking original articles, clinical trials, and comprehensive reviews exploring novel mechanisms and treatments that rewire the TME of malignant primary and secondary brain tumors, priming the immune system for immunological tumor cell death, and/or leveraging novel combination therapies which lead to increased tumor cell death, decreased tumor burden, and prolonged survival.
Dr. Lam C. Fred
Dr. Cecile Maire
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- immuno-oncology
- primary brain tumors
- metastatic brain tumors
- neuro-oncology
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