Special Issue "Advances in Borderline Personality Disorder: From Early Detection to Treatment"

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Psychiatric Diseases".

Deadline for manuscript submissions: 15 January 2024 | Viewed by 736

Special Issue Editor

Centro Psicologia Dinamica, Universitas Mercatorum, 00186 Rome, Italy
Interests: affective neuroscience; emotion regulation; psychotherapy; psychopathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Borderline personality disorder (BPD) is a complex disorder with large inter-individual variability in symptom profiles, which may include impaired relatedness (unstable relationships with others, identity disturbance, and chronic emptiness), affective dysregulation (affective liability, excessive anger, and efforts to avoid abandonment), and behavior dysregulation (impulsivity, suicidality, and self-injurious behavior). The problematic nature of BPD is characterized by self-mutilation, suicide attempts, addictions, and episodes of depression, anxiety, and aggression, which produce substantial healthcare-related and social-related costs. Psychotherapy is considered the primary treatment for BPD, and this is effective in reducing overall borderline personality disorder severity. Affective neurosciences have shown functional impairment associated with BPD in the default mode network (DMN), the salience network (SN), and the central executive network (CEN), accounting for disturbances in emotion regulation, social cognition, and all emotion-related functions. Consistently, early evidence has reported effects of treatments in these neural systems. The scope of this Special Issue is to provide a venue for the dissemination of research findings from the study of brain mechanisms in BPD and its treatment, including studies focused on concepts that may have clinical implications for the treatment of BPD (for example, emotion regulation/dysregulation, self-harm, social cognition, and others). We encourage the submission of original articles based on experimental research and neuroimaging studies applying novel techniques, as well as review articles and meta-analyses, which may enhance the understanding of processes and mechanisms underlying and maintaining BPD.

Dr. Irene Messina
Guest Editor

Manuscript Submission Information

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  • borderline
  • psychotherapy
  • neuroimaging
  • treatment
  • early detection

Published Papers (1 paper)

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“Holding in Anger” as a Mediator in the Relationship between Attachment Orientations and Borderline Personality Features
Brain Sci. 2023, 13(6), 878; https://doi.org/10.3390/brainsci13060878 - 29 May 2023
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Insecure attachment and difficulties in regulating anger have both been put forward as possible explanations for emotional dysfunction in borderline personality (BP). This study aimed to test a model according to which the influence of attachment on BP features in a subclinical population [...] Read more.
Insecure attachment and difficulties in regulating anger have both been put forward as possible explanations for emotional dysfunction in borderline personality (BP). This study aimed to test a model according to which the influence of attachment on BP features in a subclinical population is mediated by anger regulation. In a sample of 302 participants, BP features were assessed with the Borderline features scale of the Personality Assessment Inventory (PAI-BOR), attachment was measured with the Experiences in Close Relationships-12 (ECR-12), and trait anger and anger regulation were assessed with the State and Trait Anger Expression Inventory-2 (STAXI-2). The results indicated that anger suppression emerged as a significant mediator of the associations between both anxious and avoidant attachment and BP traits, while anger control resulted as a marginal mediator in the association between attachment avoidance and BP. Suppressing anger may reflect different forms of cognitive or behavioural avoidance of anger, which may differ on the basis of attachment orientations. We argue that these results may have important clinical implications: the promotion of anger regulation in BP should be considered a critical treatment goal. Full article
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