Advances in Parkinsonian Syndromes
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: closed (15 December 2021) | Viewed by 24308
Special Issue Editors
Interests: parkinsonian syndromes; neurodegenerative diseases
Interests: Parkinson’s disease; neuron; neuroprotection; neuroregeneration; neuroinflammation; neurodegeneration; biomarkers; protein aggregation; alpha-synuclein; translational therapies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Parkinsonian syndromes are a heterogeneous group of neurodegenerative diseases that differ significantly from one another in terms of associated pathology and pathogenesis, clinical course, and prognosis. They include Parkinson´s disease (PD), multiple system atrophy (MSA), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD), as well as rare genetically determined diseases. We are currently experiencing a high level of clinical scientific progress in this field. Large-scale clinico-pathological examinations have led to a more precise description of the clinical spectrum of these diseases. Imaging and laboratory markers (e.g. structural and functional MRI, FDG- and Tau-PET, CSF and blood biomarkers) are of particular research interest and will enable a more precise and earlier differential diagnosis and progression monitoring of patients with parkinsonian syndromes. The latest genetic, epigenetic and biochemical modalities allow more detailed insights into the etiology and pathogenesis. From a therapeutic point of view, new options for disease-modifying interventions have emerged from neurobiological insights. In light of these developments, this Special Issue aims at presenting the latest advances related to clinical, pathogenetic, diagnostic, and therapeutic aspects of parkinsonian syndromes. We therefore welcome contributions that provide new insights into the above-mentioned topics.
Dr. Gesine Respondek
Prof. Dr. Lars Tönges
Guest Editors
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Keywords
- parkinsonian syndromes
- neurodegeneration
- biomarker
- natural history
- differential diagnosis
- progression trajectories
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