Prevention and Intervention for Neonatal Brain Injury
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (30 May 2019)
Special Issue Editor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neonatal brain injury is a significant problem in term and preterm infants, marked by acute cellular toxicity and prolonged modifications in neuroimmunological signaling resulting in brain tissue loss and a range of motor, cognitive and other behavioral impairments that persist through adulthood. There are a number of known risk factors for neonatal brain injury including, intrauterine infection, maternal drug use, genetic history of autoimmune dysfunction and other birth complications. However, preventing and treating injury during the dynamic process of brain assembly presents unique challenges for preclinical researchers and the development of therapeutic interventions. Despite the challenges, in recent years both molecular and behavioral intervention approaches have shown promise for improving neuropathological and/or behavioral disorders linked to neonatal brain injury.
In this Special Issue, we are seeking original submissions of research or review articles from authors investigating a variety of prevention and/or intervention approaches in translational model organisms or human clinical research. Submissions are encouraged from researchers studying immunological and other molecular therapeutics aimed at targeting cell death, to those evaluating early behavioral intervention approaches designed to promote plasticity and/or mitigate cognitive/behavioral impairments later in life. Our aim is to assemble an issue that incorporates diverse preclinical and clinical approaches to prevention and intervention for neonatal brain injury.
Dr. Steven Threlkeld
Guest Editor
Manuscript Submission Information
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Keywords
- Neonatal Hypoxia-Ischemia
- Behavioral Intervention
- Pharmacology
- Preventative Care
- Immunotherapy
- Cellular Therapy
- Cognitive Intervention
- Sensory Intervention
- Neuronal Survival
- Neuronal Plasticity
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