Prevention and Intervention for Neonatal Brain Injury

Dear Colleagues,

Neonatal brain injury is a significant problem in term and preterm infants, marked by acute cellular toxicity and prolonged modifications in neuroimmunological signaling resulting in brain tissue loss and a range of motor, cognitive and other behavioral impairments that persist through adulthood. There are a number of known risk factors for neonatal brain injury including, intrauterine infection, maternal drug use, genetic history of autoimmune dysfunction and other birth complications. However, preventing and treating injury during the dynamic process of brain assembly presents unique challenges for preclinical researchers and the development of therapeutic interventions. Despite the challenges, in recent years both molecular and behavioral intervention approaches have shown promise for improving neuropathological and/or behavioral disorders linked to neonatal brain injury.

In this Special Issue, we are seeking original submissions of research or review articles from authors investigating a variety of prevention and/or intervention approaches in translational model organisms or human clinical research. Submissions are encouraged from researchers studying immunological and other molecular therapeutics aimed at targeting cell death, to those evaluating early behavioral intervention approaches designed to promote plasticity and/or mitigate cognitive/behavioral impairments later in life. Our aim is to assemble an issue that incorporates diverse preclinical and clinical approaches to prevention and intervention for neonatal brain injury. 

Dr. Steven Threlkeld
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.