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Brain Sciences
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Hot Topics in Stress-Related Mental Health Disorders
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Hot Topics in Stress-Related Mental Health Disorders

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropsychiatry".

Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 4909

Special Issue Editor

Dr. Sung Joon Cho

E-Mail Website
Guest Editor
1. Department of Psychiatry, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Republic of Korea
2. Workplace Mental Health Institute, Kangbuk Samsung Hospital, Seoul 03181, Republic of Korea
Interests: mood disorder; anxiety disorder; schizophrenia; stress; social and community psychiatry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Stress permeates every facet of contemporary life, emanating from work pressures, daily routines, and unexpected occurrences. Consequently, the prevalence of stress-related mental disorders, including anxiety, depression, and posttraumatic stress disorder (PTSD), has seen a marked increase. These conditions not only jeopardize mental well-being but also impose a significant burden on physical health, drawing escalating attention from the public and medical professionals alike.

Research efforts have focused on addressing the challenges posed by these disorders. Physical activity has emerged as a potential solution, linked with stress reduction and building resilience, which may partly mediate relationships between depression, stress, and health outcomes. Recent neuroscience findings, including biomarkers and neurotransmitters, shed light on the pathophysiology of stress-related mental disorders as well as the anti-inflammatory effects of physical activity including HPA axis balance, neuroprotection, monoamine regulation, and neuroimmune function.

This Special Issue covers the “Effects of Physical Activity on Stress and Resilience”, ranging from biological mechanisms to innovative physical treatment strategies. We extend a warm invitation for contributions to this Special Issue, encompassing fundamental and applied scientific methodologies. Your submissions promise to propel our understanding forward and offer valuable insights into the current state and future trajectories of stress-related mental health disorder research, addressing a challenge with profound socio-economic implications.

Sincerely,

Dr. Sung Joon Cho
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stress disorders
  • traumatic
  • stress response
  • resilience
  • physical activity
  • biomarkers
  • epigenomics
  • BDNF

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Published Papers (3 papers)

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15 pages, 1101 KiB  
Article
A Preliminary Investigation of a Conceptual Model Describing the Associations Between Childhood Maltreatment and Alcohol Use Problems
by Nayani Ramakrishnan, Sujaiya Tiba, Abby L. Goldstein and Suzanne Erb
Brain Sci. 2024, 14(11), 1081; https://doi.org/10.3390/brainsci14111081 - 29 Oct 2024
Viewed by 909
Abstract
Background/Objectives: Childhood maltreatment has been linked to numerous adverse outcomes in adulthood, including problem substance use. However, not all individuals exposed to childhood maltreatment develop substance use problems, indicating the role of other factors in influencing this outcome. Past work suggests that adverse [...] Read more.
Background/Objectives: Childhood maltreatment has been linked to numerous adverse outcomes in adulthood, including problem substance use. However, not all individuals exposed to childhood maltreatment develop substance use problems, indicating the role of other factors in influencing this outcome. Past work suggests that adverse early life experiences, including childhood maltreatment, lead to neurobiological changes in frontolimbic functions that, in turn, result in altered stress and reward responses, heightened impulsivity, affect dysregulation, and, ultimately, increased risk for maladaptive behaviors such as substance use. The aim of this preliminary investigation using cross-sectional data was to test associations between these factors in the relationship between childhood maltreatment and alcohol use problems in a sample of emerging adults. Methods: Emerging adults (18–30 years old) who identified as regular drinkers (i.e., drinking at least 2–4 times in the past month) were recruited from a crowd-sourcing platform (Prolific) as well as community samples. Participants completed online standardized questionnaires assessing reward sensitivity and responsiveness, impulsivity, emotion regulation, and alcohol consequences. Results: Path analyses demonstrated good fit for the data (SRMR = 0.057, RMSEA = 0.096, 90% CI [0.055, 0.142], CFI = 0.957). Childhood maltreatment was associated with reward responsiveness (β = −0.026, Z = −4.222, p < 0.001) and emotion dysregulation (β = 0.669, Z = 9.633, p < 0.001), which in turn was associated with urgency and, subsequently, alcohol consequences (β = 0.758, Z = 7.870, p < 0.001). Conclusions: Although these findings are preliminary, the current study is one of the first to test a comprehensive model addressing the relationship between childhood maltreatment and alcohol use problems. The findings have the potential to inform treatment strategies that target motivation and goal-directed action for reducing and managing consequences associated with childhood maltreatment. Future research should test the model using longitudinal data to address the limitations of a cross-sectional study and assess temporal associations between constructs. Full article
(This article belongs to the Special Issue Hot Topics in Stress-Related Mental Health Disorders)
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11 pages, 663 KiB  
Article
Sex Differences in the Association between Prolonged Sitting Time and Anxiety Prevalence among Korean Adults
by Eunsoo Kim, Chul-Hyun Park, Hyun-Seung Lee, Mi Yeon Lee and Sung Joon Cho
Brain Sci. 2024, 14(7), 729; https://doi.org/10.3390/brainsci14070729 - 20 Jul 2024
Cited by 1 | Viewed by 2451
Abstract
Sex differences in the effect of prolonged sitting time on anxiety symptoms have not yet been explored. This study examined the sex-specific association between prolonged sitting time and anxiety prevalence in Korean adults. Community-dwelling adults aged >18 years who underwent a cross-sectional structured [...] Read more.
Sex differences in the effect of prolonged sitting time on anxiety symptoms have not yet been explored. This study examined the sex-specific association between prolonged sitting time and anxiety prevalence in Korean adults. Community-dwelling adults aged >18 years who underwent a cross-sectional structured study survey of physical activity and mental health tests were enrolled as part of the Kangbuk Samsung Hospital Cohort Study from 2012 to 2019. The prevalence of anxiety was evaluated using the Clinically Useful Anxiety Outcome Scale (CUXOS) questionnaire. The mean daily sitting time was 7.9 ± 3.4 h in men and 6.8 ± 3.6 h in women. After adjustments for possible confounding factors, the adjusted mean CUXOS score was the highest in participants sitting for ≥10 h, followed by 5–9 h, and <5 h, in that order. In the post-hoc Bonferroni analysis, there were significant differences in the adjusted mean CUXOS scores in group comparisons. A multivariate logistic regression analysis was conducted after adjusting for potential confounding factors. A prolonged sitting time was positively associated with an increased prevalence of anxiety in both men and women, with stronger associations in women than in men. It is necessary to prevent anxiety by adjusting or reducing sitting time in adults, especially women. Full article
(This article belongs to the Special Issue Hot Topics in Stress-Related Mental Health Disorders)
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16 pages, 524 KiB  
Systematic Review
The Connection Between Stress and Women’s Smoking During the Perinatal Period: A Systematic Review
by M. Carmen Míguez, Yara Queiro, Cristina M. Posse and Alba Val
Brain Sci. 2025, 15(1), 13; https://doi.org/10.3390/brainsci15010013 - 26 Dec 2024
Viewed by 828
Abstract
Introduction. In women, smoking during pregnancy and the postpartum period has important consequences for maternal and infant health, and interventions to assist smoking cessation during this period are essential. Although smoking has been associated with the presence of mental health problems, few studies [...] Read more.
Introduction. In women, smoking during pregnancy and the postpartum period has important consequences for maternal and infant health, and interventions to assist smoking cessation during this period are essential. Although smoking has been associated with the presence of mental health problems, few studies addressing the factors associated with perinatal smoking have examined the role of stress. The aim of this review was to identify the relationships between the presence of stress and smoking during pregnancy and the postpartum period. Method. A literature search of the PsycInfo, Pubmed and Web of Science databases was carried out to identify relevant articles published between January 2013 and June 2024. A total of 15 studies that met the inclusion criteria were selected for review. Results. Twelve of the studies analysed the relationship between stress and smoking during pregnancy, two studies involved the postpartum period, and one study included both periods. Diverse instruments were used to assess stress, although the PSS-14 was the most commonly used. Eleven of the studies found a relationship between stress and smoking in the perinatal period, with stress being a predictor of smoking. Conclusions. The findings highlight the need to consider stress management when developing effective interventions to help women quit smoking during pregnancy and maintain abstinence in the postpartum period. Full article
(This article belongs to the Special Issue Hot Topics in Stress-Related Mental Health Disorders)
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